Less common side effects include
- low blood pressure,
- eye problems,
- fecal incontinence,
- muscle pain,
- speech problems,
- ringing in the ears (tinnitus), and
Dronabinol is a controlled substance because it may be abused.
GENERIC AVAILABLE: Yes
PREPARATIONS: Oral capsules: 2.5, 5, and 10 mg
STORAGE: Dronabinol capsules should be stored in a cool location between 8 C and 15 C (46 F and 59 F ) or in the refrigerator. Capsules should not be frozen.
For appetite stimulation in AIDS patients
- The general recommended starting dose is 2.5 mg by mouth twice daily, before lunch and dinner.
- Patients who are having difficulty tolerating this dosage may take 2.5 mg once a day in the evening or at bedtime.
- In patients who are tolerating dronabinol well, the dose may be slowly increased up to a maximum dose of 20 mg per day.
For nausea and vomiting
- 5 mg per meter-squared of body surface (5 mg/m2) should be administered 1-3 hours before chemotherapy followed by repeated administration every 2 to 4 hours after chemotherapy for a total of 4 to 6 doses per day.
- If needed, the dosage may be increased in 2.5 mg/m2 increments to a maximum of 15 mg/m2 per dose.
Although no drug-drug interactions were identified during clinical trials conducted by the manufacturer, dronabinol should be used cautiously with other medications that are known to interact with cannabinoids.
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