dopamine (hydrochloride; Intropin - Discontinued in the US)

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Charles Patrick Davis, MD, PhD
    Charles Patrick Davis, MD, PhD

    Charles Patrick Davis, MD, PhD

    Dr. Charles "Pat" Davis, MD, PhD, is a board certified Emergency Medicine doctor who currently practices as a consultant and staff member for hospitals. He has a PhD in Microbiology (UT at Austin), and the MD (Univ. Texas Medical Branch, Galveston). He is a Clinical Professor (retired) in the Division of Emergency Medicine, UT Health Science Center at San Antonio, and has been the Chief of Emergency Medicine at UT Medical Branch and at UTHSCSA with over 250 publications.

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GENERIC NAME: dopamine hydrochloride

DISCONTINUED BRANDS: Intropin

DRUG CLASS AND MECHANISM: Dopamine is a chemical produced by our body and it has several functions. Dopamine works as a neurotransmitter (chemical that nerves use to communicate) in the brain. It is also converted to norepinephrine, another neurotransmitter. Dopamine increases heart rate and heart muscle contractions. It also causes increases in blood pressure. The FDA approved dopamine in February 1974.

PRESCRIBED FOR: Dopamine is prescribed to correct hemodynamic status in patients with shock syndrome due to heart attack (myocardial infarction), trauma, open-heart surgery, renal failure, congestive heart failure, and other causes of shock syndrome. This means dopamine may be capable of improving urine flow, blood pressure, blood flow to vital organs, and improving heart function in patients with shock syndrome.

SIDE EFFECTS: Side effects of dopamine may include:

  • increased heart rate,
  • abnormal heart rhythm,
  • increased or decreased blood pressure,
  • disordered breathing,
  • nausea,
  • vomiting,
  • headache, and
  • increased blood urea nitrogen.

PRESCRIPTION: Yes

GENERIC AVAILABLE: Yes

PREPARATIONS: Additive solutions for IV infusion: 40, 80, 160 mg/ml. Infusion Solution: 80, 160, 320, mg/100 ml

Medically Reviewed by a Doctor on 12/22/2015

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