docusate (Correctol, Colace, Dulcolax, Phillips Liquid-Gels, and many others) (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

STORAGE: Tablets should be stored at room temperature between 15 C to 30 C (59 F to 86 F).

PRESCRIBED FOR: Docusate is used as a stool softener to treat and prevent constipation.

DOSING:

  • Adult (≥ 12 years): The recommended oral dose is 50 to 500 mg/day in 1 to 4 divided doses. The recommended rectal dose is 50 to100 mg of docusate liquid added to enema fluid.
  • Pediatric: The recommended dose for infants and children <3 years is 10 to 40 mg/day in 1 to 4 divided doses. The recommended dose in children between the ages of 3 to 6 is 20 to 60 mg/day in 1 to 4 divided doses. The recommended dose in children between the ages of 6 to 12 is 40-150 mg/day in 1 to 4 divided doses.

DRUG INTERACTIONS: No significant drug to drug interactions have been reported with docusate salts. Administration of docusate with mineral oil is not recommended because docusate may increase the absorption of mineral oil which may lead to serious allergic reactions.

PREGNANCY: Use of docusate for the short-term treatment of constipation during pregnancy is generally considered to be safe. As docusate is not absorbed into the body, they are generally considered to be safe in pregnancy. However, all pregnant patients should ask their doctor or pharmacists before starting treatment with docusate.

NURSING MOTHERS: Docusate is generally considered to be safe during breastfeeding.

SIDE EFFECTS: Docusate salts rarely cause side effects since they are not absorbed into the body. Occasional side effects may include stomach cramping, diarrhea, intestinal obstruction, and rash. Throat irritation has occurred in some patients after taking liquid formulations of docusate orally.

REFERENCE: FDA Prescribing Information.


Medically Reviewed by a Doctor on 11/14/2014


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