docusate (Correctol, Colace, Dulcolax, Phillips Liquid-Gels, and many others)

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Charles Patrick Davis, MD, PhD
    Charles Patrick Davis, MD, PhD

    Charles Patrick Davis, MD, PhD

    Dr. Charles "Pat" Davis, MD, PhD, is a board certified Emergency Medicine doctor who currently practices as a consultant and staff member for hospitals. He has a PhD in Microbiology (UT at Austin), and the MD (Univ. Texas Medical Branch, Galveston). He is a Clinical Professor (retired) in the Division of Emergency Medicine, UT Health Science Center at San Antonio, and has been the Chief of Emergency Medicine at UT Medical Branch and at UTHSCSA with over 250 publications.

Constipation Myths & Facts

PRESCRIPTION: No

GENERIC AVAILABLE: Yes

PREPARATIONS:

  • Docusate Calcium: Softgel Capsules: 240 mg
  • Docusate Sodium: 100 mg capsules; 100 mg liquid filled capsules; 50 mg/5 ml oral solution; 50 mg/5 ml oral suspension; 60 mg/15 ml syrup; 100 mg tablets; 100 mg rectal enema suspension; 282 mg rectal enema suspension.

STORAGE: Tablets should be stored at room temperature between 15 C to 30 C (59 F to 86 F).

DOSING:

  • Adult (≥ 12 years): The recommended oral dose is 50 to 500 mg/day in 1 to 4 divided doses. The recommended rectal dose is 50 to100 mg of docusate liquid added to enema fluid.
  • Pediatric: The recommended dose for infants and children <3 years is 10 to 40 mg/day in 1 to 4 divided doses. The recommended dose in children between the ages of 3 to 6 is 20 to 60 mg/day in 1 to 4 divided doses. The recommended dose in children between the ages of 6 to 12 is 40-150 mg/day in 1 to 4 divided doses.

DRUG INTERACTIONS: No significant drug to drug interactions have been reported with docusate salts. Administration of docusate with mineral oil is not recommended because docusate may increase the absorption of mineral oil which may lead to serious allergic reactions.

PREGNANCY: Use of docusate for the short-term treatment of constipation during pregnancy is generally considered to be safe. As docusate is not absorbed into the body, they are generally considered to be safe in pregnancy. However, all pregnant patients should ask their doctor or pharmacists before starting treatment with docusate.

NURSING MOTHERS: Docusate is generally considered to be safe during breastfeeding.

REFERENCE: FDA Prescribing Information.

Medically Reviewed by a Doctor on 7/30/2015

Quick GuideDigestive Disorders: Constipation Myths and Facts

Digestive Disorders: Constipation Myths and Facts
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