- What is docetaxel, and how does it work (mechanism of action)?
- What brand names are available for docetaxel?
- Is docetaxel available as a generic drug?
- Do I need a prescription for docetaxel?
- What are the side effects of docetaxel?
- What is the dosage for docetaxel?
- Which drugs or supplements interact with docetaxel?
- Is docetaxel safe to take if I'm pregnant or breastfeeding?
- What else should I know about docetaxel?
What is the dosage for docetaxel?
Docetaxel is given intravenously. Doses range from 60 mg/m2 to 100 mg/m2 every 3 weeks in combination with other chemotherapy agents. Dexamethasone also is administered prior to docetaxel to reduce the severity of fluid retention and occurrence of hypersensitivity reactions.
Which drugs or supplements interact with docetaxel?
Drugs that reduce the activity of liver enzymes that break down docetaxel and other drugs increase the blood levels of docetaxel and increase its side effects. Examples include ketoconazole (Nizoral, Extina, Xolegel, Kuric), erythromycin (E-Mycin, Eryc, Ery-Tab, Pce, Pediazole, Ilosone), and protease inhibitors (for example, ritonavir [Norvir]).
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