docetaxel, Taxotere, Docefrez
Omudhome Ogbru, PharmD
Omudhome Ogbru, PharmD
Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.
Medical and Pharmacy Editor:
GENERIC NAME: docetaxel
BRAND NAME: Taxotere, Docefrez
DRUG CLASS AND MECHANISM: Docetaxel is a drug that is used primarily for treating breast cancer. Docetaxel works by attacking cancer cells. Every cell in the body contains a supporting structure (almost like a skeleton) called the microtubular network. If this "skeleton" is changed or damaged, the cell can't grow or reproduce. Docetaxel makes the "skeleton" in cancer cells unnaturally stiff, so that these cells can no longer grow.
GENERIC AVAILABLE: No
PREPARATIONS: Injection Concentrate: 20 mg/0.5 ml, 80 mg/2 ml; Injection (Powder): 20 mg/vial, 80 mg/vial
STORAGE: Docetaxel concentrate should be stored between 2 and 25 C (36 to 77 F), and the powder should be stored between 2 and 8 C (36 F and 46 F). They should be retained in their original package to protect them from light.
PRESCRIBED FOR: Docetaxel is used for the treatment of patients with locally advanced or metastatic breast cancer after failure of prior chemotherapy; second-line treatment of patients with non-small cell lung cancer after failure of platinum-based chemotherapy; prostate cancer; gastric adenocarcinoma; and squamous cell carcinoma of the head and neck.
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