disulfiram, Antabuse

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GENERIC NAME: disulfiram

BRAND NAME: Antabuse



USES: Disulfiram is used of treating alcoholism. It is used in combination with supportive care and psychotherapy.

Disulfiram should never be given to a patient who is intoxicated, or without his or her full knowledge. Relatives of patients should be advised about this warning also.

Patients should be fully informed about the disulfiram-alcohol reaction and must be strongly warned about drinking while taking disulfiram. Patients should avoid alcohol in all forms, including alcohol in sauces, vinegars, cough mixtures, mouth wash, aftershave lotions, and back rubs.

Disulfiram may cause a reaction with alcohol up to 14 days after ingestion.

Disulfiram should be used cautiously in patients with diabetes, hypothyroidism, epilepsy, cerebral damage, nephritis, and hepatic impairment.

Disulfiram should not be given to people with severe heart disease, people allergic to disulfiram, and people with psychosis.


When alcohol is consumed by a patient taking disulfiram, effects include:

Common side effects of disulfiram include:

Possible serious side effects of disulfiram include:

Medically Reviewed by a Doctor on 1/19/2016

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