dimethyl fumarate (Tecfidera)

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GENERIC NAME: dimethyl fumarate

BRAND NAME: Tecfidera

DRUG CLASS AND MECHANISM: Dimethyl fumarate is an oral disease-modifying agent used for treating relapsing forms of multiple sclerosis (MS). Teriflunomide (Aubagio), Interferon beta-1a (Avonex), interferon beta-1b (Betaseron), glatiramer acetate (Copaxone), interferon beta-1b (Extavia), fingolimod (Gilenya), mitoxantrone (Novantrone), interferon beta-1a (Rebif), and natalizumab (Tysabri) are other disease modifying agents for multiple sclerosis. Although the exact mechanism of how dimethyl fumarate works is unknown, it is thought to have protective effects on the nervous system and anti-inflammatory properties. Dimethyl fumarate prevents the immune cells from attacking the central nervous system. Dimethyl fumarate reduces the number of annual relapses rate. The FDA approved dimethyl fumarate in March 2013.

PRESCRIPTION: Yes

GENERIC AVAILABLE: No

PREPARATIONS: Delayed-release capsules: 120 mg and 240 mg

STORAGE: Capsules should be stored at 15 C to 30 C (59 F to 86 F). The capsules should be stored in the original container and protected from light.

Medically Reviewed by a Doctor on 8/19/2014



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