dimethyl fumarate (Tecfidera)

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Charles Patrick Davis, MD, PhD
    Charles Patrick Davis, MD, PhD

    Charles Patrick Davis, MD, PhD

    Dr. Charles "Pat" Davis, MD, PhD, is a board certified Emergency Medicine doctor who currently practices as a consultant and staff member for hospitals. He has a PhD in Microbiology (UT at Austin), and the MD (Univ. Texas Medical Branch, Galveston). He is a Clinical Professor (retired) in the Division of Emergency Medicine, UT Health Science Center at San Antonio, and has been the Chief of Emergency Medicine at UT Medical Branch and at UTHSCSA with over 250 publications.

The Effects of Multiple Sclerosis

GENERIC NAME: dimethyl fumarate

BRAND NAME: Tecfidera

DRUG CLASS AND MECHANISM: Dimethyl fumarate is an oral disease-modifying agent used for treating relapsing forms of multiple sclerosis (MS). Teriflunomide (Aubagio), Interferon beta-1a (Avonex), interferon beta-1b (Betaseron), glatiramer acetate (Copaxone), interferon beta-1b (Extavia), fingolimod (Gilenya), mitoxantrone (Novantrone), interferon beta-1a (Rebif), and natalizumab (Tysabri) are other disease modifying agents for multiple sclerosis. Although the exact mechanism of how dimethyl fumarate works is unknown, it is thought to have protective effects on the nervous system and anti-inflammatory properties. Dimethyl fumarate prevents the immune cells from attacking the central nervous system. Dimethyl fumarate reduces the number of annual relapses rate. The FDA approved dimethyl fumarate in March 2013.

PRESCRIPTION: Yes

GENERIC AVAILABLE: No

PREPARATIONS: Delayed-release capsules: 120 mg and 240 mg

STORAGE: Capsules should be stored at 15 C to 30 C (59 F to 86 F). The capsules should be stored in the original container and protected from light.

PRESCRIBED FOR: Dimethyl fumarate is used for the treatment of patients (adults) with relapsing forms of multiple sclerosis (MS).

Medically Reviewed by a Doctor on 8/19/2014

Quick GuideMultiple Sclerosis Pictures Slideshow: Causes, Symptoms and Treatment

Multiple Sclerosis Pictures Slideshow: Causes, Symptoms and Treatment
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