- What is dimethyl fumarate, and how does it work (mechanism of action)?
- What brand names are available for dimethyl fumarate?
- Is dimethyl fumarate available as a generic drug?
- Do I need a prescription for dimethyl fumarate?
- What are the side effects of dimethyl fumarate?
- What is the dosage for dimethyl fumarate?
- Which drugs or supplements interact with dimethyl fumarate?
- Is dimethyl fumarate safe to take if I'm pregnant or breastfeeding?
- What else should I know about dimethyl fumarate?
What is dimethyl fumarate, and how does it work (mechanism of action)?
Dimethyl fumarate is an oral disease-modifying agent used for treating relapsing forms of multiple sclerosis (MS). Teriflunomide (Aubagio), Interferon beta-1a (Avonex), interferon beta-1b (Betaseron), glatiramer acetate (Copaxone), interferon beta-1b (Extavia), fingolimod (Gilenya), mitoxantrone (Novantrone), interferon beta-1a (Rebif), and natalizumab (Tysabri) are other disease modifying agents for multiple sclerosis. Although the exact mechanism of how dimethyl fumarate works is unknown, it is thought to have protective effects on the nervous system and anti-inflammatory properties. Dimethyl fumarate prevents the immune cells from attacking the central nervous system. Dimethyl fumarate reduces the number of annual relapses rate. The FDA approved dimethyl fumarate in March 2013.
What brand names are available for dimethyl fumarate?
Is dimethyl fumarate available as a generic drug?
GENERIC AVAILABLE: No
Do I need a prescription for dimethyl fumarate?
What are the side effects of dimethyl fumarate?
The most common side effects associated with dimethyl fumarate treatment are flushing, abdominal pain, diarrhea, and nausea. A decrease in white blood cell count also occurs. Patients should check their baseline white blood cell count or have a recently completed blood cell count (CBC) (within 6 months) before starting treatment. Increase in liver enzymes has also been reported in clinical studies.
Quick GuideMultiple Sclerosis (MS) Symptoms and Treatment
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