GENERIC NAME: DIHYDROERGOTAMINE - NASAL (dye-HI-dro-er-GOT-uh-meen)
BRAND NAME(S): Migranal
Warning | Medication Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage
WARNING: Infrequently, a very serious, life-threatening decrease in the amount of blood supply to the hands and feet (peripheral ischemia) and rarely to the brain can occur when this medication is taken with drugs that affect liver metabolism (e.g., potent CYP 3A4 enzyme inhibitors). Do not take this medication with macrolide antibiotics (e.g., erythromycin, clarithromycin, troleandomycin), protease inhibitors (e.g., ritonavir, nelfinavir, indinavir, amprenavir, saquinavir), azole antifungals (e.g., ketoconazole, itraconazole).
USES: This medication is used to treat migraine headache attacks. It is not used to prevent migraines from occurring.
HOW TO USE: Use exactly as directed and do not use more often than prescribed. Learn the proper technique for assembly and use of the nasal spray device. Spray applicator must be primed (pumped 4 times) before use. Consult your pharmacist. This drug is meant to be absorbed through the nostril. Do not inhale deeply through the nose while spraying. Use at the first sign of headache. The usual dose is one spray into each nostril. Repeat one spray into each nostril 15 minutes later. Full relief usually begins in 30 minutes. Four sprays total (2 sprays into each nostril) are advised for a single attack. In the U.S., 6 sprays per day (3 sprays in each nostril) and 8 sprays per week (4 sprays in each nostril) are the maximum doses that should be used. Do not use daily on a regular basis. Consult your doctor or pharmacist regarding how and when to treat additional migraine attacks. Avoid eating grapefruit or drinking grapefruit juice at any time while using this medication unless your doctor instructs you otherwise. Other "ergot" drugs (e.g., ergotamine), methysergide or "triptan-type" drugs (e.g., sumatriptan) should not be used within 24 hours of this drug.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
- Migraine - Learn about migraine headache including symptoms such as intense throbbing pain in the temple area of head. Migraine triggers vary from person to person.
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