dihydroergotamine - injection, D.H.E.45 (cont.)
DRUG INTERACTIONS: See also Warning section and How to Use section.Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist firstThis drug should not be used with the following medications because very serious interactions may occur: delavirdine, efavirenz, sibutramine, drugs listed in Warning section.If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting this medication.Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially: certain beta blockers (e.g., propranolol), decongestants (e.g., pseudoephedrine), dopamine, drugs affecting liver enzymes that remove ergotamine from your body (such as fluconazole, fluoxetine, fluvoxamine, clotrimazole, nefazodone, zileuton), nicotine (e.g., nicotine gum, nicotine patches, tobacco), nitrates (e.g., isosorbide, nitroglycerin), other ergot alkaloids (e.g., methysergide).If you also take "triptan" migraine drugs (e.g., sumatriptan, rizatriptan), you will need to separate your "triptan" dose from your dose of this medication to reduce the risk of serious side effects. Ask your doctor how long you should wait between your doses of these drugs.Check the labels on all your medicines (e.g., cough-and-cold products, diet aids, other migraine medications) because they may contain ingredients that could increase your heart rate or blood pressure. Ask your pharmacist about the safe use of those products.This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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