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dihydroergotamine - injection, D.H.E.45 (cont.)

DRUG INTERACTIONS: See also Warning and How to Use sections.Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.Some products that may interact with this drug include: bronchodilators/decongestants/stimulants (such as epinephrine, pseudoephedrine, methylphenidate, amphetamine).Other medications can affect the removal of dihydroergotamine from your body, which may affect how dihydroergotamine works. Examples include boceprevir, mifepristone, telaprevir, HIV NNRTIs (such as delavirdine, efavirenz), a certain combination HIV medication (elvitegravir/cobicistat/emtricitabine/tenofovir), certain antidepressants (such as nefazodone, SSRIs such as fluoxetine/paroxetine/fluvoxamine), among others.If you also take "triptan" migraine drugs (e.g., sumatriptan, rizatriptan), you will need to separate your "triptan" dose from your dose of this medication to reduce the risk of serious side effects. Ask your doctor how long you should wait between your doses of these drugs.Check the labels on all your medicines (e.g., cough-and-cold products, diet aids, other migraine medications) because they may contain ingredients that could increase your heart rate or blood pressure. Ask your pharmacist about the safe use of those products.

Medically Reviewed by a Doctor on 4/16/2014


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