GENERIC NAME: DIFENOXIN/ATROPINE - ORAL (DYE-fen-OX-in/AT-roe-peen)
BRAND NAME(S): Motofen
USES: This medication is used to treat diarrhea. It helps to decrease the number and frequency of bowel movements. It works by slowing the movement of the intestines. Difenoxin is similar to narcotic pain relievers, but it acts mainly to slow the gut. Atropine belongs to a class of drugs known as anticholinergics, which help to dry up body fluids and also slow gut movement.
HOW TO USE: Take this medication by mouth, usually after each loose stool, or every 3 or 4 hours as needed or as directed by your doctor. Dosage is based on your medical condition and response to therapy. For adults, do not take more than 8 milligrams of difenoxin in any 24-hour period. If you need to continue treatment once your diarrhea is controlled, your doctor may direct you to lower your dosage. Do not increase your dose, take it more often, or use it for longer than prescribed.It is important that you drink the proper amount of fluids and minerals (electrolytes) to prevent loss of body water (dehydration). Tell your doctor immediately if you develop signs of dehydration (e.g., extreme thirst, decreased urination, muscle cramps, weakness, fainting). You may also need to change to a bland diet during this time to reduce irritation to your stomach/intestines. Consult your doctor or pharmacist for more information.This medication may cause withdrawal reactions, especially if it has been used regularly for a long time or in high doses. In such cases, withdrawal symptoms (such as stomach cramps, nausea, vomiting) may occur if you suddenly stop using this medication. To prevent withdrawal reactions, your doctor may reduce your dose gradually. Consult your doctor or pharmacist for more details, and report any withdrawal reactions immediately.Inform your doctor if your condition does not improve after 2 days.
Quick GuideDigestive Disease Myths Pictures Slideshow: Common Misconceptions
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Need help identifying pills and medications?
Use the pill identifier tool on RxList.