didanosine, Videx, Videx EC

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

HIV/AIDS Myths and Facts

PRESCRIBED FOR: Didanosine is used for the treatment of HIV infection in adults and children.

SIDE EFFECTS: The most severe side effects of didanosine are:

Symptoms of peripheral neuropathy are tingling, numbness and pain in the feet or hands.

Other important side effects include:



PREPARATIONS: Capsules (Extended Release): 125, 200, 250, and 400 mg. Solution: 10 mg/ml

STORAGE: Capsules and unmixed powder should be stored at room temperature, 15 C to 30 C (59 F to 86 F). The powder may be stored in the refrigerator at 2 C to 8 C (36 F to 46 F for up to 30 days after it is mixed with water.

DOSING: Adults weighing 60 kg or more should receive 400 mg once daily of the capsules or 200 mg twice daily of the powder. Adults weighing less than 60 kg require 250 mg once daily of the capsules and 125 mg twice daily of the powder.

Didanosine should be administered on an empty stomach because food reduces the absorption of didanosine by as much as 46%.

DRUG INTERACTIONS: Didanosine powder contains an antacid which reduces the absorption of tetracycline (for example, Vibramycin, Minocin), ketoconazole (Nizoral), fluoroquinolone antibiotics (for example, ciprofloxacin [Cipro], Floxin), and other drugs that need stomach acid for absorption. Therefore, these drugs should be administered at least two hours before or after administration of didanosine solution.

Medically Reviewed by a Doctor on 6/17/2015

Quick GuideHIV AIDS Pictures Slideshow: Myths and Facts on Symptoms and Treatments

HIV AIDS Pictures Slideshow: Myths and Facts on Symptoms and Treatments
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