diclofenac, Voltaren, Cataflam, Voltaren-XR, Cambia (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

PREGNANCY: Like other NSAIDs, diclofenac is generally avoided during pregnancy because it may affect the cardiovascular system of the fetus.

NURSING MOTHERS: It is not known whether diclofenac is excreted in breast milk.

SIDE EFFECTS: The most common side effects of diclofenac involve the gastrointestinal system. It can cause ulcerations, abdominal burning, pain, cramping, nausea, gastritis, and even serious gastrointestinal bleeding and liver toxicity. Sometimes, stomach ulceration and bleeding can occur without any abdominal pain. Black tarry stools, weakness, and dizziness upon standing may be the only signs of internal bleeding. Rash, kidney impairment, ringing in the ears, and lightheadedness are also seen. People who are allergic to other NSAIDs should not use diclofenac. NSAIDs reduce the flow of blood to the kidneys and impair function of the kidneys. The impairment is most likely to occur in patients with already reduced kidney function or congestive heart failure, and use of NSAIDs in these patients should be done cautiously. Individuals with asthma are more likely to experience allergic reactions to diclofenac and other NSAIDs. Fluid retention, blood clots, heart attacks, hypertension, and heart failure also have been associated with the use of NSAIDs.

Reference: FDA Prescribing Information


Last Editorial Review: 3/26/2013



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