GENERIC NAME: dexmethylphenidate hydrochloride
BRAND NAME: Focalin, Focalin XR
DRUG CLASS AND MECHANISM: Dexmethylphenidate is a medication used for treating attention deficit hyperactivity disorder (ADHD). It is chemically similar to methylphenidate (Ritalin, Concerta). It stimulates the central nervous system (CNS or brain) in a manner that is similar to amphetamines; however, its actions are milder than amphetamines. It stimulates the brain by increasing the level of neurotransmitters, dopamine and norepinephrine, in the brain neurotransmitters are chemicals produced by nerves that are released and attach to other nearby nerves as a means of communication among nerves). The exact mechanism of action of the drug in people with ADHD is unknown. FDA approved dexmethylphenidate extended-release capsules in May 2005.
GENERIC AVAILABLE: Yes
PREPARATIONS: Tablet: 2.5, 5, 10 mg. Capsules (extended-release) dexmethylphenidate: 5, 10, 15, 20, 25, 30, 35, and 40 mg
STORAGE: Store dexmethylphenidate between temperatures of 15 C to 30 C (59 F to 86 F).
- The dose of immediate release tablets is 2.5 mg twice daily and increase by 2.5 or 5 mg weekly if needed. The maximum dose is 20 mg daily.
- Methylphenidate-naive patients: Start with 10 mg extended release capsules by mouth once daily in the morning and adjust the dose weekly in 10 mg increments. The maximum dose is 40 mg daily.
- Patients currently using methylphenidate: The starting dose of extended release capsules is one-half the total daily dose of methylphenidate. Patients currently taking immediate-release dexmethylphenidate tablets may be switched to same daily dose of extended-release capsules.
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