dexamethasone injection (Baycadron, Decadron [Discontinued], Dexamethasone Intensol)

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Charles Patrick Davis, MD, PhD
    Charles Patrick Davis, MD, PhD

    Charles Patrick Davis, MD, PhD

    Dr. Charles "Pat" Davis, MD, PhD, is a board certified Emergency Medicine doctor who currently practices as a consultant and staff member for hospitals. He has a PhD in Microbiology (UT at Austin), and the MD (Univ. Texas Medical Branch, Galveston). He is a Clinical Professor (retired) in the Division of Emergency Medicine, UT Health Science Center at San Antonio, and has been the Chief of Emergency Medicine at UT Medical Branch and at UTHSCSA with over 250 publications.

Understanding COPD

GENERIC NAME: dexamethasone injection

BRAND NAMES: Baycadron, Decadron (Discontinued), Dexamethasone Intensol

DRUG CLASS AND MECHANISM: Dexamethasone is a synthetic (created by a chemical processes) corticosteroid hormone like prednisone, betamethasone, and triamcinolone. More specifically, dexamethasone is a glucocorticoid hormone, which means that it has anti-inflammatory effects, as well as the ability to affect blood glucose use, fat breakdown, and bone development depending on where it binds in the body. Dexamethasone reduces inflammation by preventing immune cells, such as neutrophils, from migrating to the site of action, reducing the release of inflammatory signals, as well as decreasing how well substances may pass in and out of the blood vessels. It also has anti-vomiting properties (antiemetic). The FDA approved dexamethasone in 1958.

PRESCRIPTION: Yes

GENERIC AVAILABLE: Yes

PREPARATIONS: Injection solution: 4 mg/mL and 10 mg/ml; 1 mg/ml

STORAGE: Dexamethasone should be stored as intact vials at room temperature, between 20 C to 25 C (68 F to 77 F). Protect from light and heat. Do not freeze. If diluted, use within 24 hours.

PRESCRIBED FOR: Dexamethasone injection is prescribed for vomiting, as well as for a variety of diseases where blocking the immune system is important. This includes allergies, skin conditions, endocrine, hematologic, inflammatory, neoplastic, nervous system, renal, respiratory, rheumatic, and autoimmune diseases. It is also used to manage cerebral edema and chronic swelling.

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