GENERIC NAME: dexamethasone injection
BRAND NAMES: Baycadron, Decadron (Discontinued), Dexamethasone Intensol
DRUG CLASS AND MECHANISM: Dexamethasone is a synthetic (created by a chemical processes) corticosteroid hormone like prednisone, betamethasone, and triamcinolone. More specifically, dexamethasone is a glucocorticoid hormone, which means that it has anti-inflammatory effects, as well as the ability to affect blood glucose use, fat breakdown, and bone development depending on where it binds in the body. Dexamethasone reduces inflammation by preventing immune cells, such as neutrophils, from migrating to the site of action, reducing the release of inflammatory signals, as well as decreasing how well substances may pass in and out of the blood vessels. It also has anti-vomiting properties (antiemetic). The FDA approved dexamethasone in 1958.
GENERIC AVAILABLE: Yes
PREPARATIONS: Injection solution: 4 mg/mL and 10 mg/ml; 1 mg/ml
STORAGE: Dexamethasone should be stored as intact vials at room temperature, between 20 C to 25 C (68 F to 77 F). Protect from light and heat. Do not freeze. If diluted, use within 24 hours.
PRESCRIBED FOR: Dexamethasone injection is prescribed for vomiting, as well as for a variety of diseases where blocking the immune system is important. This includes allergies, skin conditions, endocrine, hematologic, inflammatory, neoplastic, nervous system, renal, respiratory, rheumatic, and autoimmune diseases. It is also used to manage cerebral edema and chronic swelling.
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