Topicort (desoximetasone topical)

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.


  • A thin film of Topicort should be applied to the affected areas twice daily.
  • Using Topicort beyond 4 weeks is not advisable.

DRUG INTERACTIONS: There are no drug interactions listed for this product.


  • Topicort has not been adequately evaluated in pregnant women. Pregnant patients should not use corticosteroids extensively, in large amounts, or for prolonged periods of time.
  • It is not known if Topicort is secreted in breast milk.


  • Cream: 0.05, 0.25%
  • Gel: 0.05%
  • Ointment: 0.25%
  • Spray: 0.25%

STORAGE: Store Topicort at room temperature between 15 C - 30 C (59 F - 86 F)


  • Desoximetasone is a synthetic (man-made) corticosteroid that is used on the skin (topically). The naturally-occurring corticosteroid is cortisol or hydrocortisone produced by the adrenal gland. Corticosteroids have potent anti-inflammatory actions and also suppress the immune response.
  • The FDA approved desoximetasone in March 1982.

REFERENCE: FDA Prescribing Information

Medically Reviewed by a Doctor on 8/30/2016

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