desloratadine, Clarinex (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

GENERIC AVAILABLE: Yes

PREPARATIONS: Tablets: 5 mg. Orally Disintegrating (RediTabs): 2.5 and 5 mg. Syrup: 0.5 mg/1mL

STORAGE: Tablets and syrup should be stored at 25 C (77 F).

PRESCRIBED FOR: Desloratadine is used for the treatment of allergies and chronic urticaria (hives) in adults and children 6 months of age or older.

DOSING: The recommended dose for adults and children 12 years or older is 5 mg daily.

For children 6 to 11 years of age the dose is 2.5 mg of the syrup or 2.5 mg of the RediTabs once daily.

Children 12 months to 5 years old should receive 1.25 mg of the syrup once daily and children 6 to 11 months old are treated with 1 mg of syrup once daily.

Desloratadine can be taken with or without food.

DRUG INTERACTIONS: Ketoconazole (Nizoral, Extina, Xolegel, Kuric), erythromycin, azithromycin (Zithromax), fluoxetine (Prozac), and cimetidine (Tagamet) increase blood levels of desloratadine by reducing the elimination of desloratadine by liver enzymes.

PREGNANCY: Desloratadine has not been studied in pregnant women.

NURSING MOTHERS: Desloratadine passes into breast milk and should therefore be used with caution in women who are breastfeeding.

SIDE EFFECTS: The most common side effects of desloratadine are headache, dizziness, nausea, weakness, sore throat, dry mouth, muscle pain, painful menstruation, and sleepiness.

Reference: FDA Prescribing Information


Last Editorial Review: 4/24/2012



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