desloratadine, Clarinex, Clarinex Reditabs

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

GENERIC NAME: desloratadine

BRAND NAME: Clarinex, Clarinex Reditabs

DRUG CLASS AND MECHANISM: Desloratadine is an oral, long-acting antihistamine that is similar chemically to loratadine (Claritin). It is used to treat the symptoms caused by histamine. Histamine is a chemical that is responsible for many of the signs and symptoms of allergic reactions, for example, swelling of the lining of the nose, sneezing, and itchy eyes. Histamine is released from histamine-storing cells (mast cells) and then attaches to other cells that have receptors for histamine. The attachment of the histamine to the receptors causes the cells to be "activated," releasing other chemicals which produce the effects that we associate with allergy. Desloratadine blocks one type of receptor for histamine (the H1 receptor) and thus prevents activation of H1 receptor-containing cells by histamine. Desloratadine does not readily enter the brain from the blood and, therefore, causes less drowsiness (sedation). It is a member of a small family of non-sedating antihistamines which includes loratadine (Claritin), cetirizine (Zyrtec), fexofenadine (Allegra), and levocetirizine (Xyzal). Desloratadine was approved by the FDA in December 2001.

PRESCRIBED FOR: Desloratadine is used for the treatment of allergies and chronic urticaria (hives) in adults and children 6 months of age or older.

SIDE EFFECTS: The most common side effects of desloratadine are:

Medically Reviewed by a Doctor on 4/3/2015

Quick GuideBad Bugs: Identify Bug Bites From Mosquitos, Spiders and More

Bad Bugs: Identify Bug Bites From Mosquitos, Spiders and More
FDA Logo

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

RxList Logo

Need help identifying pills and medications?

Use the pill identifier tool on RxList.

Subscribe to MedicineNet's Allergy and Asthma Newsletter

By clicking Submit, I agree to the MedicineNet's Terms & Conditions & Privacy Policy and understand that I may opt out of MedicineNet's subscriptions at any time.

Health Solutions From Our Sponsors