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February 10, 2012
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dornase alfa solution - inhalation, Pulmozyme

GENERIC NAME: DORNASE ALFA SOLUTION - INHALATION (DOOR-naze AL-fa)

BRAND NAME(S): Pulmozyme

Medication Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage

USES: This medication is used to improve breathing and reduce the risk of lung infections in people with cystic fibrosis. It is used along with other treatments for this disease (e.g., chest physical therapy, medications, nutritional supplements). Dornase alfa is the same as a substance (DNase I enzyme) that is naturally produced by the body. It works in the airways by decreasing stickiness/thickness of mucus so that it can be cleared from the lungs more easily.

HOW TO USE: This medication is inhaled into the lungs using special breathing equipment, usually once or twice daily or as directed by your doctor. A health care professional will show you the proper way to prepare the medication and use the equipment. If you are unclear about any of the instructions, ask your health care professional.Dosage is based on your medical condition and response to treatment. Do not increase your dose or take this medication more frequently than prescribed. Your condition will not improve faster and the risk for side effects may be increased.Use this medication regularly to get the most benefit from it. To help you remember, use it at the same times each day.

SIDE EFFECTS: Sore/dry throat and hoarseness may occur. Eye redness/irritation may also infrequently occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.Tell your doctor immediately if this unlikely but serious side effect occurs: chest pain.A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, unusual trouble breathing.This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.In the US -Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.




Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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