GENERIC NAME: deoxycholic acid
BRAND NAME: Kybella
DRUG CLASS AND MECHANISM: Deoxycholic acid (Kybella) is an injectable medication used for reducing fat in the submental region of the face (below the chin). Deoxycholic acid destroys the cell membrane of fat cells causing fat cells to die. Reducing the number of fat cells reduces fat under the chin. It should not be injected in other tissues because it also destroys other cells. In clinical studies 43% of people who received deoxycholic acid achieved a 10% reduction in submental fat volume after six or fewer treatment. Only 5% of people who received placebo achieved a 10% reduction in submental fat. Deoxycholic acid was approved by the FDA in April, 2015.
PRESCRIBED FOR: Deoxycholic acid is used for improving the appearance of moderate to severe fullness associated with submental fat (double chin) in adults. It is not approved for reducing fat in other areas of the body.
SIDE EFFECTS: Side effects of deoxycholic acid include:
- injection site swelling,
- hematoma (collection of blood in tissues),
- skin redness (erythema),
- difficulty swallowing (dysphagia)
- high blood pressure, and
Injecting deoxycholic acid outside the submental area can cause damage to surrounding tissues. Injecting deoxycholic acid into the dermis may cause skin ulceration. Injecting deoxycholic acid into or in close proximity to the facial nerve may cause asymmetric smile and facial muscle weakness.
GENERIC AVAILABLE: No
PREPARATIONS: Injection: 10 mg/ml in 2 ml vials for single-patient use.
Quick GuidePlastic Surgery: Before and After Photos of Cosmetic Surgeries
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Need help identifying pills and medications?
Use the pill identifier tool on RxList.