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GENERIC NAME: DENILEUKIN DIFTITOX - INJECTABLE (den-ih-LEW-kin DIFF-teh-tox)

BRAND NAME(S): Ontak

Warning | Medication Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage | Medical Alert

WARNING: Denileukin is a potent medication that should only be given in a proper facility (e.g., hospital, clinic) with the recommended safety/monitoring equipment available. Consult your doctor.

USES: Denileukin diftitox is used to treat a certain type of cancer (recurrent or persistent cutaneous T-cell lymphoma/CTCL).

HOW TO USE: This medication has very specific directions for use. Follow all instructions for proper handling (e.g., thawing and swirling the vials), mixing, and diluting with the correct IV fluids. If you have any questions regarding the use of this medication, consult your pharmacist. Do not shake the container/vial. Give this medication by vein (IV) over at least 15 minutes in a preservative-free saline solution. Usually this drug is given once daily for 5 days only, or as directed by your doctor. The dosage and length of treatment is based on your weight, medical condition, and response to therapy. The dose cycle (every day for 5 days) is usually repeated every 3 weeks, or as determined by your doctor. Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid. When used for an extended period, this medication may not work as well and may require different dosing. Consult your doctor. Learn how to store and discard needles and medical supplies safely. Consult your pharmacist.

SIDE EFFECTS: Flu-like symptoms (e.g., fever, chills, sore throat, unusual weakness, muscle aches), nausea, vomiting, diarrhea, constipation, dizziness, nervousness, lightheadedness, cough, runny nose, or headache may occur. If any of these effects persist or worsen, notify your doctor. Tell your doctor immediately if any of these serious side effects occur: swelling (edema), loss of appetite, weight loss, muscle pain/cramps, pain/swelling/redness at the injection site, rash, itching, trouble breathing, chest pain. Tell your doctor immediately if any of these unlikely but serious side effects occur: unusual sweating/flushing, unusually fast/irregular heartbeat, joint pain, back pain, confusion, trouble sleeping, trouble swallowing. Tell your doctor immediately if any of these highly unlikely but very serious side effects occur: easy bleeding or bruising, persistent sore throat and fever, red or pink-colored urine, severe stomach pain, change in amount of urine, pain in the lower legs. A serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction include: rash, itching, swelling, severe dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.




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denileukin diftitox-injectable, Ontak

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