Dengue Fever

  • Medical Author:
    John P. Cunha, DO, FACOEP

    John P. Cunha, DO, is a U.S. board-certified Emergency Medicine Physician. Dr. Cunha's educational background includes a BS in Biology from Rutgers, the State University of New Jersey, and a DO from the Kansas City University of Medicine and Biosciences in Kansas City, MO. He completed residency training in Emergency Medicine at Newark Beth Israel Medical Center in Newark, New Jersey.

  • Medical Editor: Melissa Conrad Stöppler, MD
    Melissa Conrad Stöppler, MD

    Melissa Conrad Stöppler, MD

    Melissa Conrad Stöppler, MD, is a U.S. board-certified Anatomic Pathologist with subspecialty training in the fields of Experimental and Molecular Pathology. Dr. Stöppler's educational background includes a BA with Highest Distinction from the University of Virginia and an MD from the University of North Carolina. She completed residency training in Anatomic Pathology at Georgetown University followed by subspecialty fellowship training in molecular diagnostics and experimental pathology.

Read about dengue fever symptoms and signs.

Dengue Symptoms and Signs

Primary symptoms of dengue appear three to 15 days after the mosquito bite and include the following:

  • high fever and severe headache,
  • with severe pain behind the eyes that is apparent when trying to move the eyes.

Other associated symptoms are:

  • joint pain,
  • muscle and bone pain,
  • rash,
  • and mild bleeding.

Many affected people complain of low back pain.

Quick GuideTravel Health Pictures Slideshow: Vaccines & Preventing Diseases Abroad

Travel Health Pictures Slideshow: Vaccines & Preventing Diseases Abroad

Dengue fever facts

  • Dengue fever is a disease caused by a family of viruses that are transmitted by mosquitoes.
  • Symptoms of dengue fever include severe joint and muscle pain, swollen lymph nodes, headache, fever, exhaustion, and rash. The presence of fever, rash, and headache (the "dengue triad") is characteristic of dengue fever.
  • Dengue is prevalent throughout the tropics and subtropics.
  • Dengue fever is caused by a virus, and there is no specific medicine or antibiotic to treat it. For typical dengue fever, the treatment is directed toward relief of the symptoms (symptomatic treatment).
  • The acute phase of the illness with fever and muscle pain lasts about one to two weeks.
  • Dengue hemorrhagic fever (DHF) is a specific syndrome that tends to affect children under 10 years of age. This complication of dengue causes abdominal pain, hemorrhage (bleeding), and circulatory collapse (shock).
  • The prevention of dengue fever requires control or eradication of the mosquitoes carrying the virus that causes dengue.
  • A vaccine for dengue fever was approved in April 2016 for use in dengue-endemic areas. Continue Reading
Reviewed on 4/28/2016
References
REFERENCES:

Anwar, Sarah. "First Dengue Vaccine Approved By WHO After Twenty Years of Clinical Studies." ContagionLive.com. Apr. 19, 2016. <http://www.contagionlive.com/news/first-dengue-vaccine-is-approved-by-who-after-twenty-years-of-clinical-studies?utm_source=Informz&utm_medium=Contagion+Live&utm_campaign=Contagion_Live_
Trending_2_4-19-16>.

Canada. Public Health Agency of Canada. "Dengue Fever: Global Update." June 3, 2011. <http://www.phac-aspc.gc.ca/tmp-pmv/thn-csv/dengue-eng.php>.

Canada. Public Health Agency of Canada. "Dengue in South East Asia." Aug. 23, 2007. <http://www.phac-aspc.gc.ca/tmp-pmv/2007/dengue070823_e.html>.

"Dengue Fever in Key West." Florida Department of Health. <http://www.doh.state.fl.us/Environment/medicine/arboviral/Dengue_FloridaKeys.html>.

Dengue Vaccine Initiative. <http://www.denguevaccines.org/>.

Effler, P.V., et al. "Dengue Fever, Hawaii, 2001-2002." Emerg Infec Dis 11.5 May 2005: 742-749. <http://www.ncbi.nlm.nih.gov/pubmed/15890132>.

Hendrick, Bill. "FDA OKs Test for Dengue Fever." WebMD.com. Apr. 13, 2011. <http://www.webmd.com/news/20110413/fda-oks-test-for-dengue-fever>.

New Zealand. Auckland Regional Public Health Service. "Dengue Fever, Zika & Chikungunya." September 2015. <http://www.arphs.govt.nz/health-information/communicable-disease/dengue-fever-zika-chikungunya#.VgB53HvBdgo>.

Seet, Raymond C.S., Amy M.L. Quek, and Erle C.H. Lim. "Post-infectious fatigue syndrome in dengue infection." Journal of Clinical Virology 38 (2007): 1-6. <http://189.28.128.102/portal/arquivos/kitdengue2/aspectosclinicos/textos/
postinfection_fatigue_syndrome.pdf>.

Shepherd, Suzanne Moore. "Dengue." Medscape.com. Oct. 5, 2015. <http://emedicine.medscape.com/article/215840-overview#a6>.

Switzerland. World Health Organization. "Dengue and Severe Dengue." April 2016.<http://www.who.int/mediacentre/factsheets/fs117/en/>.

Switzerland. World Health Organization. "Dengue vaccine research." Dec. 14, 2015. <http://www.who.int/immunization/research/development/dengue_vaccines/en/>.

Switzerland. World Health Organization. "Planning Social Mobilization and Communication for Dengue Fever Prevention and Control." <http://www.who.int/tdr/publications/publications/pdf/planning_dengue.pdf>.

Switzerland. World Health Organization. "Vector-Borne Viral Infections." <http://www.who.int/vaccine_research/diseases/vector/en/index.html>.

United States. California Department of Public Health. "Aedes aegypti and Aedes albopictus Mosquitoes." <https://www.cdph.ca.gov/HEALTHINFO/DISCOND/Pages/Aedes-albopictus-and-Aedes-aegypti-Mosquitoes.aspx>.

United States. Centers for Disease Control and Prevention. "Chikungunya." Oct. 6, 2010. <http://www.cdc.gov/ncidod/dvbid/chikungunya/>.

United States. Centers for Disease Control and Prevention. "Dengue." June 15, 2015. <http://www.cdc.gov/Dengue/>.

United States. Centers for Disease Control and Prevention. "Dengue." Oct. 28, 2010. <http://www.cdc.gov/dengue/epidemiology/index.html>.

United States. Centers for Disease Control and Prevention. "Dengue Hemorrhagic Fever --- U.S.-Mexico Border, 2005." Aug. 8, 2007. <http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5631a1.htm>.

United States. Centers for Disease Control and Prevention. "Locally Acquired Dengue -- Key West, Florida, 2009-2010." Morbidity and Mortality Weekly Report 59.19 May 21, 2010: 577-581. <http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5919a1.htm>.

United States. State of Hawaii, Department of Health. "Dengue Outbreak 2015." Jan. 8, 2016. <http://health.hawaii.gov/docd/dengue-outbreak-2015/>.

"Why a Vaccine." Dengue Vaccine Initiative. <http://www.denguevaccines.org/why-a-vaccine>.

IMAGES:

1. MedicineNet

2. "Dengue" by CDC per University of South Carolina Biomedical Sciences

3. CDC

4. Getty Images

5. MedicineNet

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7. Getty Images

8. Getty Images

9. iStock

10. Getty Images

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