delavirdine, Rescriptor (cont.)
Omudhome Ogbru, PharmD
Omudhome Ogbru, PharmD
Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.
Medical and Pharmacy Editor:
PRESCRIBED FOR: Delavirdine is used together with other anti-HIV drugs for the treatment of HIV infection.
SIDE EFFECTS: The most common side effects of delavirdine are:
Other important side effects include
GENERIC AVAILABLE: No
PREPARATIONS: Tablets: 100 and 200 mg
STORAGE: Delavirdine should be stored at room temperature, 15 C to 30 C (59 F to 86 F).
DOSING: The recommended dose for adults is 400 mg three times daily. To administer as a solution four 100 mg tablets in at least 3 oz of water should stand for a few minutes. It then shoud be mixed and consumed in its entirety immediately. Delavirdine may be administered without regard to meals since food does not reduce its absorption.
DRUG INTERACTIONS: Delavirdine has many drug interactions because it reduces the activity of certain liver enzymes that breakdown many drugs, and the breakdown of delavirdine is reduced by other drugs.
Some examples of delavirdine interactions include:
PREGNANCY: The are no adequate studies of the use of delavirdine in pregnant women.
NURSING MOTHERS: It is not known whether delavirdine is secreted in breast milk. HIV infected mothers should not nurse their infants because of the risk of transmitting HIV to an infant that is not infected.
Reference: FDA Prescribing Information
Medically Reviewed by a Doctor on 6/17/2015
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