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February 10, 2010
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Dehydration

Medical Author: Benjamin C. Wedro, MD, FAAEM
Medical Editor: Melissa Conrad Stöppler, MD

Doctor to Patient

Exercise-Associated Hyponatremia: Who's at Risk?

Medical Author: Melissa Conrad Stöppler, MD
Medical Editor: William C. Shiel Jr., MD, FACP, FACR

Are you in danger of developing hyponatremia?We've all learned that fluid replacement is critical to replace fluids lost when exercising, but drinking pure water exclusively isn't the safest choice for those who participate in very strenuous or long-duration exercise.

When significant amounts of fluid are lost through high-intensity exercise, replacement with water alone can lead to a chemical imbalance in the body and deficiencies in electrolytes, which are nutrients critical for organ functioning. The electrolytes in our body include sodium, potassium, chloride, calcium and phosphate, but sodium is the substance of most concern when replacing fluids lost through exercising.

Hyponatremia is a condition in which the body's stores of sodium are too low, and this condition can result from drinking extreme amounts of water. Hyponatremia can lead to confusion, lethargy, agitation, seizures, and in extreme cases, even death. Early symptoms are nonspecific and subtle and may include disorientation, nausea, or muscle cramps. The symptoms of hyponatremia may also mimic those of dehydration, so athletes experiencing these symptoms may be given more water to drink, further worsening the condition.


Doctor to Patient

What is dehydration?

The majority of the body is made up of water, with up to 75% of the body's weight due to H2O. Most of the water is found within the cells of the body (intracellular space). The rest is found in what is referred to as the extracellular space, which consists of the blood vessels (intravascular space) and the spaces between cells (interstitial space).

Total body water = intracellular space + intravascular space + interstitial space

Dehydration occurs when the amount of water leaving the body is greater than the amount being taken in. The body is very dynamic and always changing. This is especially true with water in the body. We lose water routinely when:

  • we breathe and humidified air leaves the body;

  • we sweat to cool the body; and

  • we urinate or have a bowel movement to rid the body of waste products.

In a normal day, a person has to drink a significant amount of water to replace this routine loss.

If intravascular (within the blood vessels) water is lost, the body can compensate somewhat by shifting water from cells into the blood vessels, but this is a very short-term solution. Signs and symptoms of dehydration will occur quickly if the water is not replenished.

The body is able to monitor the amount of fluid it needs to function. The thirst mechanism signals the body to drink water when the body is dry. As well, hormones like anti-diuretic hormone (ADH) work with the kidney to limit the amount of water lost in the urine when the body needs to conserve water.

Dynamic Picture of Rehydration

Dynamic Picture of Dehydration

What causes dehydration?

Dehydration occurs because there is too much water lost, not enough water taken in, or most often a combination of the two.

  • Diarrhea: Diarrhea is the most common reason a person loses excess water. A significant amount of water can be lost with each bowel movement. Worldwide, more than four million children die each year because of dehydration from diarrhea.

  • Vomiting: Vomiting can also be a cause of fluid loss and it is difficult for a person to replace water by drinking it if they are unable to tolerate liquids.

  • Sweat: The body can lose significant amounts of water when it tries to cool itself by sweating. Whether the body is hot because of the environment (for example, working in a warm environment), intense exercising in a hot environment, or because a fever is present due to an infection; the body uses a significant amount of water in the form of sweat to cool itself. Depending upon weather conditions, a brisk walk will generate up to 16 ounces of sweat (a pound of water).

  • Diabetes: In people with diabetes, elevated blood sugar levels cause sugar to spill into the urine and water then follows, which can cause significant dehydration. For this reason, frequent urination and excessive thirst are among the symptoms of diabetes.

  • Burns: Burn victims become dehydrated because water seeps into the damaged skin. Other inflammatory diseases of the skin are also associated with fluid loss.

  • Inability to drink fluids: The inability to drink adequately is the other potential cause of dehydration. Whether it is the lack of availability of water or the lack of strength to drink adequate amounts, this, coupled with routine or extraordinary water losses can compound the degree of dehydration.


Next: What are the signs and symptoms of dehydration? »

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Dehydration

What is a kidney stone?

A kidney stone is a hard, crystalline mineral material formed within the kidney or urinary tract. Kidney stones are a common cause of blood in the urine and often severe pain in the abdomen, flank, or groin. Kidney stones are sometimes called renal calculi. One in every 20 people develops a kidney stone at some point in their life.

The condition of having kidney stones is termed nephrolithiasis. Having stones at any location in the urinary tract is referred to as urolithiasis.

What causes kidney stones?

Kidney stones form when there is a decrease in urine volume and/or an excess of stone-forming substances in the urine. The most common type of kidney stone contains calcium in combination with either oxalate or phosphate. Other chemical compounds that can form stones in the urinary tract include uric acid and the amino acid cystine.

Dehydration from reduced fluid intake...

Read the Kidney Stones article »











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