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February 10, 2012
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daunorubicin citrate liposome - injection, Daunoxome

GENERIC NAME: DAUNORUBICIN CITRATE LIPOSOME - INJECTION (dawn-oh-REWB-eh-sin SIH-trate lye-poe-SEW-mull)

BRAND NAME(S): Daunoxome

Warning | Medication Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage

WARNING: This medication may infrequently result in serious (rarely fatal) heart problems (including heart failure). This may occur both during treatment or months to years after treatment is completed. The risk of heart problems is affected by your dose, medical history (including previous heart disease, radiation treatment to the chest area), and previous use of this and other drugs (including doxorubicin). Tell your doctor immediately if you notice symptoms such as very fast/irregular heartbeat, shortness of breath, or swelling ankles/feet.

Daunorubicin may cause certain severe blood and bone marrow disorders (low red blood cells/white blood cells/platelets). This can affect your body's ability to stop bleeding or fight infection. Tell your doctor immediately if you develop easy bleeding/bruising or signs of infection (e.g., fever, chills, persistent sore throat).

Very rarely, people with cancer who are treated with this type of medication have developed other cancers (e.g., secondary leukemia). The risk may be increased when this medication is given with certain anti-cancer drugs or radiation treatment. Consult your doctor for more details.

Before starting treatment with this medication, tell your doctor if you have liver or kidney problems. Your dose may need to be adjusted.

This medication may cause symptoms including back pain, flushing, and chest tightness, usually during the first 5 minutes of injection into a vein. If you notice any of these symptoms, tell your doctor or nurse immediately. If the injection is temporarily stopped and then given more slowly, the symptoms will not usually return.

USES: This medication is used to treat a certain type of cancer (Kaposi's sarcoma). It belongs to a class of drugs known as anthracyclines and works by slowing or stopping the growth of cancer cells.

HOW TO USE: This medication is given by injection slowly into a vein by a health care professional as directed by your doctor. Dosage is based on your medical condition, body size, and response to treatment.If this medication accidentally leaks into the skin/muscle around the injection site, it may cause severe damage. Tell your doctor immediately if you notice redness, pain, or swelling at or near the injection site.If this medication touches your skin, immediately wash the area well with soap and water. Caregivers should take precautions (e.g., wear gloves) to prevent contact with the patient's urine and other body fluids.Drink plenty of fluids while using this medication unless otherwise directed by your doctor. Doing so helps decrease the risk of certain side effects (e.g., increased uric acid).




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You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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daunorubicin citrate liposome - injection, Daunoxome

What is cancer?

Cancer is the uncontrolled growth of abnormal cells anywhere in a body. The abnormal cells are termed cancer cells, malignant cells, or tumor cells. Many cancers and the abnormal cells that compose the cancer tissue are further identified by the name of the tissue that the abnormal cells originated from (for example, breast cancer, lung cancer, colon cancer). Cancer is not confined to humans; animals and other living organisms can get cancer. Below is a schematic that shows normal cell division and how when a cell is damaged or altered without repair to its system, the cell usually dies. Also shown is what can occur when such damaged or unrepaired cells do not die and become cancer cells and proliferate with uncontrolled growth; a mass of cancer cells develop. Frequently, cancer cells can break away from this original mass of cells, travel through the blood and lymph systems, and lodge in other organs where they can again repeat the ...

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