dasatinib, Sprycel (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

Dasatinib increases the blood concentration of simvastatin (Zocor) by reducing the activity of enzymes that break down simvastatin in the liver. This may increase the side effects of simvastatin. Dasatinib may interact with other drugs that are broken down in a similar way as simvastatin.

PREGNANCY: Dasatinib is harmful to the fetus and should not be used during pregnancy.

NURSING MOTHERS: It is unknown whether dasatinib is excreted in human milk.

SIDE EFFECTS: Common side effects include fluid retention, headache, diarrhea, constipation, weakness, nausea and vomiting, abdominal distention, weight loss or gain, rash, itching, chills, dizziness, and muscle pain. Serious side effects include fever associated with reduced white blood cells, reduced platelets, and red blood cell counts, infection, stomach or intestinal bleeding, bleeding in the brain, heart failure, and fluid in the lungs.

Last Editorial Review: 10/13/2011 7:31:16 PM

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