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- What is dasatinib, and how does it work (mechanism of action)?
- What brand names are available for dasatinib?
- Is dasatinib available as a generic drug?
- Do I need a prescription for dasatinib?
- What are the side effects of dasatinib?
- What is the dosage for dasatinib?
- Which drugs or supplements interact with dasatinib?
- Is dasatinib safe to take if I'm pregnant or breastfeeding?
- What else should I know about dasatinib?
What is dasatinib, and how does it work (mechanism of action)?
: Dasatinib is an oral medication used for treating chronic myeloid leukemia and acute lymphoblastic leukemia. It is classified as a kinase inhibitor. Kinase inhibitors include Erlotinib (Tarceva), gefitinib (Iressa), imatinib (Gleevec), nilotinib (Tasigna), pazopanib (Votrient), sunitinib (Sutent), and vandetanib (Caprelsa). Kinase inhibitors prevent the growth of tumors by reducing the action of proteins that control cell division, growth, and survival. These proteins are usually present in larger quantities or are more active in cancer cells. By reducing the activity of these proteins, growth and survival of cancer cells are reduced. The FDA approved dasatinib in June 2006.
What brand names are available for dasatinib?
Is dasatinib available as a generic drug?
GENERIC AVAILABLE: No
Do I need a prescription for dasatinib?
What are the side effects of dasatinib?
Common side effects are:
- fluid retention,
- nausea and vomiting,
- abdominal distention,
- weight loss or gain,
- dizziness, and
- muscle pain.
Other important and serious side effects of dasatinib include:
- fever associated with reduced white blood cells,
- reduced platelets,
- reduced blood cell counts,
- stomach or intestinal bleeding,
- bleeding in the brain,
- heart failure, and
- fluid in the lungs.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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