USES: This medication is used to treat a certain type of skin disorder (dermatitis herpetiformis). It is also used with other drugs to treat Hansen's disease. Dapsone belongs to a class of drugs known as sulfones. It works by decreasing swelling (inflammation) and stopping the growth of bacteria.This medication will not work for viral infections (e.g., common cold, flu). Unnecessary use or misuse of any antibiotic can lead to its decreased effectiveness.OTHER This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional.This drug may also be used to treat or prevent a certain lung infection due to HIV (pneumocystis pneumonia), to prevent a certain brain infection due to HIV (toxoplasmosis), and to treat skin conditions in certain immune system disorders (e.g., systemic lupus erythematosus-SLE).
HOW TO USE: Take this medication by mouth with or without food, usually once daily or as directed by your doctor.Medications for heartburn/reducing stomach acid (e.g., large amounts of antacids, ranitidine, famotidine), or didanosine may prevent full absorption of dapsone into your bloodstream, possibly reducing its effectiveness. Therefore, separate your dose of dapsone from your doses of any of these products by at least 2 hours. Ask your doctor or pharmacist for more details.If you are taking dapsone for a skin disorder, your doctor may start you on a low dose of dapsone and gradually adjust your dose to control your disease. If you are taking this medication to treat Hansen's disease or to prevent infections due to HIV, the drug is usually taken for years or for life.Dosage is based on your medical condition and response to treatment. In children, the dosage is also based on age and weight.Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day.Tell your doctor if your condition worsens.
HIV (human immunodeficiency virus) is the cause of AIDS (acquired immunodeficiency syndrome). HIV is a type of virus called a retrovirus, which infects humans when it comes in contact with a break in the skin or tissues such as those that line the vagina, anal area, mouth, or eyes.
Systemic lupus erythematosus is a condition characterized by chronic inflammation of body tissues caused by autoimmune disease. Lupus can cause disease of the skin, heart, lungs, kidneys, joints, and nervous
system. When only the skin is involved, the condition is called discoid lupus.
When internal organs are involved, the condition is called systemic lupus
erythematosus (SLE).
Leprosy (Hansen's disease) is a disfiguring disease caused by infection with Mycobacterium leprae bacteria. The disease is spread from person to person through nasal secretions or droplets. Symptoms and signs of leprosy include numbness, loss of temperature sensation, painless ulcers, eye damage, loss of digits, and facial disfigurement. Leprosy is treated with antibiotics and the dosage and length of time of administration depends upon which form of leprosy the patient has.
Relapsing polychondritis is an uncommon, chronic disorder of the cartilage that is characterized by recurrent episodes of inflammation of the cartilage of various tissues of the body. Tissues containing cartilage that can become inflamed include the ears, nose, joints, spine, and windpipe (trachea). Tissues that have a biochemical makeup similar to that of cartilage such as the eyes, heart, and blood vessels, can also be affected. Nonsteroidal antiinflammatory medications (NSAIDs) is used as treatment for mild cases of the disease. Steroid-related medications also are usually required.
Leprosy is a disease caused by the bacteria Mycobacterium leprae, which causes
damage to the skin and the peripheral nervous system. The disease develops
slowly (from six months to 40 years!) and results in skin lesions and deformities,
most often affecting the cooler places on the body (for example, eyes, nose,
earlobes, hands, feet, and testicles). The skin lesions and deformities can be
very disfiguring and are the reason that infected individuals historically were considered
outcasts in many cultures. Although human-to-human transmission is the primary
source of infection, three other species can carry and (rarely) transfer M.
leprae to humans: chimpanzees, mangabey monkeys, and nine-banded armadillos. The
disease is termed a chronic granulomatous disease, similar to tuberculosis, because it produces
inflammatory nodules (granulomas) in the skin and nerves over time.
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