dapagliflozin, Farxiga

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

What is dapagliflozin, and how does it work (mechanism of action)?

Dapagliflozin (Farxiga) is an oral medication used to improve glycemia (blood glucose) control in patients with type 2 diabetes. Dapagliflozin is a sodium-glucose cotransporter (SGLT2) inhibitor. It is similar to canagliflozin (Invokana) and empagliflozin (Jardiance). SGLT2 is found in the kidney tubules and is responsible for reabsorbing the majority of glucose filtered out of the blood by the kidneys. By inhibiting SGLT2 dapagliflozin reduces the reabsorption of filtered glucose and consequently increases excretion of glucose in the urine. Dapagliflozin is not recommended for use in patients with moderate to severe kidney disease. Dapagliflozin was approved by the US FDA in January 2014.

What brand names are available for dapagliflozin?

Farxiga

Is dapagliflozin available as a generic drug?

GENERIC AVAILABLE: No

Do I need a prescription for dapagliflozin?

Yes

What are the side effects of dapagliflozin?

The most common side effects associated with dapagliflozin were:

Other reported side effects include:

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