dalfampridine, Ampyra

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GENERIC NAME: dalfampridine

BRAND NAME: Ampyra

DRUG CLASS AND MECHANISM: Ampyra is an oral medication used for treating multiple sclerosis. Its exact mechanism of action is unknown, but it is known to block movement of potassium between nerve cells. In animal studies Ampyra increased the conduction of nerve signals. The FDA approved Ampyra in December 1987.

GENERIC AVAILABLE: No.

PRESCRIPTION: Yes.

PREPARATIONS: Tablet (extended release): 10 mg

STORAGE: Ampyra should be stored at room temperature, 15 C to 30 C (59 F to 86 F).

PRESCRIBED FOR: Ampyra is used to improve walking in patients with multiple sclerosis (MS).

DOSING: The recommended dose is 10 mg twice daily with or without food about 12 hours apart. Tablets should not be divided, crushed, chewed, or dissolved.

DRUG INTERACTIONS: Drug interactions have not been identified for Ampyra.

PREGNANCY: There are no adequate studies of Ampyra in pregnant women.

NURSING MOTHERS: It is not known whether Ampyra is excreted in human milk.

SIDE EFFECTS: The most common side effect of Ampyra is urinary tract infections. Other common side effects include nausea, insomnia, dizziness, headache, and back pain. Serious side effects of Ampyra include seizures and severe allergic reactions.


Medically Reviewed by a Doctor on 11/4/2013



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