PRECAUTIONS: This medication must not be used by women who are or may become pregnant or while nursing. Because this medication can affect the production of sperm in men, a reliable form of birth control is recommended while taking this medication. Tell your doctor if you have: blood disorders, liver disease, heart disease, gout, allergies (especially drug allergies). Caution is advised when using this drug in the elderly as they may be more sensitive to the effects of the drug, especially the effect on blood cell production (myelosuppression).

DRUG INTERACTIONS: Tell your doctor of all prescription and nonprescription medication you may use. Do not start or stop any medicine without doctor or pharmacist approval.

OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.

NOTES: This medication can lower your body's ability to fight an infection. Notify your doctor if you develop any signs of an infection such as fever, sore throat, rash, or chills. Avoid touching your eyes or inside your nose without first washing your hands. Use caution with sharp objects like safety razors or nail cutters and avoid activities such as contact sports in order to lower the chance of getting cut, bruised or injured. Do not have immunizations/vaccinations without consent of your doctor, and avoid contact with people who have recently received oral polio vaccine. Regular doctor visits are important. Frequent blood tests will be done to monitor therapy.

MISSED DOSE: Do not double dose if missed. Contact your doctor.

STORAGE: Refrigerate piggyback or infusion device. Warm to room temperature before infusing. Check expiration date. Store vial at room temperature away from sunlight.

MEDICAL ALERT: Your condition can cause complications in a medical emergency. For enrollment information call MedicAlert at 1-800-854-1166 (USA), or 1-800-668-1507 (Canada).