- What is daclizumab, and how does it work?
- What brand names are available for daclizumab?
- Is daclizumab available as a generic drug?
- Do I need a prescription for daclizumab?
- What are the uses for daclizumab?
- Why is there a black box warning for daclizumab?
- What are the side effects of daclizumab?
- What is the dosage for daclizumab?
- Which drugs or supplements interact with daclizumab?
- Is daclizumab safe to use during pregnancy or while breastfeeding?
- What else should I know about daclizumab?
What are the uses for daclizumab?
- Daclizumab is used for the treatment of adult patients with relapsing forms of multiple sclerosis (MS).
- It is reserved for patients who have had an inadequate response to two or more MS drugs because of its safety profile.
Why is there a black box warning for daclizumab?
- Daclizumab can cause severe liver injury including life-threatening events, liver failure, and autoimmune hepatitis. Transaminase and bilirubin levels should be obtained before starting daclizumab, monthly during treatment, and up to 6 months after the last dose.
- It should not be used in patients with liver problems.
- This drug can cause immune-mediated disorders including skin reactions, lymphadenopathy (enlargement of lymph nodes), non-infectious colitis, and other immune-mediated disorders. These conditions may require treatment with oral or injectable corticosteroids or medication to suppress the immune system.
- Daclizumab is available only through a restricted distribution program called the ZINBRYTA REMS Program.
Medically Reviewed by a Doctor on 1/27/2017
Quick GuideMultiple Sclerosis (MS) Symptoms and Treatment
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