GENERIC NAME: DACLIZUMAB - INJECTION (dack-LIZ-you-mab)
BRAND NAME(S): Zenapax
Medication Uses | Other Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage | Medical Alert
USES: This medication is used to prevent organ rejection in patients receiving kidney transplants. This drug is used in combination with other drugs (e.g., cyclosporine and steroids).
OTHER USES: This drug may also be used for other types of organ transplants.
HOW TO USE: This medication is given by injection into a vein (IV) after proper dilution in a saline solution. The dose is given over a 15 minute period, every 14 days for a total of 5 doses, beginning no more than 24 hours before transplantation. Review all the preparation and administration instructions in the product package and ask your doctor or pharmacist if any information is unclear. Do not use if solution is cloudy or colored. Do not shake the vial. This medication should be given by a health care professional.
SIDE EFFECTS: Nausea, vomiting, constipation or diarrhea may occur. If these effects persist or worsen, notify your doctor. Report promptly: stomach pain, headache, dizziness, chest pain, arm or leg swelling, trouble breathing, coughing, sore throat, fever, poor wound healing, bleeding, muscle pain, increased thirst or hunger, cloudiness or unusual change in amount of urine. Unlikely but report promptly: bloody urine or stools, weakness, leg cramps, increased sweating, mood/mental changes, arthritis pain, pain at the site of injection. In the unlikely event you have an allergic reaction to this drug, seek medical attention immediately. Symptoms of an allergic reaction include: rash, itching, swelling, dizziness, trouble breathing. In a heart transplant study, use of daclizumab in combination with cyclosporine, mycophenolate mofetil, and corticosteroids may have infrequently caused serious reactions (sometimes death). Consult your doctor or pharmacist for more details. If you notice other effects not listed above, contact your doctor or pharmacist.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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