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November 21, 2009
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GENERIC NAME: DACARBAZINE - INJECTION (duh-KAR-buh-zeen)

BRAND NAME(S): DTIC-Dome

Warning | Medication Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage | Medical Alert

WARNING: This medication can cause severe liver problems (hepatic necrosis), or a decrease in the formation of new blood cells (hemopoietic depression). Notify your doctor immediately if you develop symptoms of an infection (such as persistent sore throat or fever), easy bruising or bleeding, nausea, dark urine, unusual fatigue, yellowing of the eyes or skin, or abdominal/stomach pain. Your doctor will monitor you closely while you are using this medication.

USES: Dacarbazine is used to treat cancer.

HOW TO USE: This is a potent medication. Use it exactly as prescribed. Dacarbazine is often used in combination with other cancer-fighting drugs. Tell your doctor or nurse immediately if you experience pain, burning or redness at the place where injected.

SIDE EFFECTS: Nausea, vomiting, flu-like symptoms (uneasiness, joint or muscle pain), flushing or numbness of face are common. Changes in diet such as eating several small meals or limiting activity may help lessen some of these effects. In some cases, drug therapy may be necessary to prevent or relieve nausea and vomiting. Temporary hair loss is another common side effect. Normal hair growth should return after treatment has ended. Tell your doctor immediately if you have any of these unlikely but serious side effects: unusual tiredness or weakness, fever, chills, sore throat, cough, lower back or side pain, painful or difficult urination, unusual bleeding or bruising, black tarry stools, blood in urine or stools, small red spots on the skin, sores in mouth or on lips. An allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include: rash, itching, swelling, dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.




Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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dacarbazine-injection, DTIC-Dome

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