dacarbazine - injection, DTIC-Dome
GENERIC NAME: DACARBAZINE - INJECTION (duh-KAR-buh-zeen)
BRAND NAME(S): DTIC-Dome
Warning |
Medication Uses | How To Use | Side Effects |
Precautions | Drug Interactions | Overdose | Notes |
Missed Dose | Storage
WARNING: This medication may often cause serious blood disorders (decreased bone marrow function leading to a low number of red blood cells, white blood cells, and platelets). These effects can cause anemia, lower your body's ability to fight an infection, and increase your risk of bleeding. Dacarbazine may also cause rare but serious liver problems. These side effects may rarely be life-threatening. Your doctor will monitor you closely while you are receiving this medication.
Tell your doctor immediately if you develop any of the following symptoms: unusual tiredness, pale skin, easy bruising/bleeding, signs of infection (e.g., fever, chills, persistent sore throat), persistent nausea/vomiting, dark urine, yellowing eyes/skin, stomach/abdominal pain.
USES: Dacarbazine is used to treat certain types of cancer, such as skin cancer that has spread (metastatic malignant melanoma) and Hodgkin's disease. It is a cancer chemotherapy drug that is used alone or with other medications to slow or stop cancer cell growth.
HOW TO USE: This medication is given by injection into a vein by a health care professional. It is given on a schedule as directed by your doctor. Dosage is based on your medical condition, body size, and response to treatment.
SIDE EFFECTS: See also Warning section.Nausea, vomiting, and loss of appetite commonly occur. Vomiting may last up to 12 hours. Your doctor may prescribe medication to prevent or relieve nausea and vomiting. Eating several small meals, not eating for 4 to 6 hours before treatment, or limiting activity may help lessen these effects. These symptoms usually decrease after 1 to 2 days. Diarrhea, flu-like symptoms (e.g., discomfort, uneasiness, body aches, headache), blurred vision, or flushing/numbness/tingling of the face may also occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.Temporary hair loss may occur. Normal hair growth should return after treatment has ended.Many people using this medication have serious side effects. However, your doctor has prescribed this drug because he or she has judged that the benefit to you is greater than the risk of side effects. Careful monitoring by your doctor may decrease your risk.If this medication leaks out of the vein into the tissue under the skin, it may cause serious tissue damage. Tell your doctor immediately if you experience pain, burning, redness, or swelling at the injection site.Tell your doctor right away if you have any serious side effects, including: mouth sores, confusion, seizures, sunburn (sun sensitivity).A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any of the following symptoms of a serious allergic reaction: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.In the US -Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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