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- Cytomegalovirus (CMV) infection facts
- What is cytomegalovirus (CMV)?
- What causes cytomegalovirus infection?
- What are the risk factors for cytomegalovirus infection?
- Is CMV contagious?
- How long is cytomegalovirus contagious?
- How is cytomegalovirus transmitted?
- What is the incubation period for cytomegalovirus?
- What are cytomegalovirus infection symptoms and signs?
- How do physicians diagnose cytomegalovirus infection?
- What is the treatment for cytomegalovirus infection?
- What is the prognosis of cytomegalovirus infection?
- What are complications of cytomegalovirus infection?
- Is it possible to prevent cytomegalovirus infection? Is there a CMV vaccine?
What is the prognosis of cytomegalovirus infection?
Most healthy children and adults who develop symptoms will recover without any complications. Fatigue may last for several months after a symptomatic infection is over. Prognosis depends on how severe the CMV infection is and the person's underlying immune system. Giving antiviral medication in people who have a very weak immune system, such as bone marrow transplant recipients, improves prognosis.
Approximately 80% of infants with congenital CMV infection grow up healthy without complications and do not need treatment with antiviral medication. However, one in five infants born with CMV infection will have permanent hearing loss and developmental disabilities. Children diagnosed with congenital CMV infection should have regular vision and hearing screenings, because early detection can improve outcomes.
What are complications of cytomegalovirus infection?
CMV rarely causes complications in healthy people. The risk of complications is higher in individuals with weakened immune systems. CMV can infect the stomach and intestines, causing fever, abdominal pain, blood in the stool, and inflammation of the colon (colitis). Inflammation can also occur in the liver (hepatitis), lung (pneumonitis), and brain (encephalitis). Infection in the eye (retinitis) can cause blindness. Newborns with congenital CMV infection can develop hearing and vision loss, mental disability, and seizures.
Is it possible to prevent cytomegalovirus infection? Is there a CMV vaccine?
Because CMV is a common virus, it is not always possible to prevent infection. Pregnant women should avoid exposure to CMV to prevent congenital CMV infection. Steps to reduce the risk of CMV infection include the following:
- Washing hands frequently for 15-20 seconds, especially when in contact with young children, changing diapers, and handling toys, or when exposed to oral secretions
- Avoiding sharing food, drinks, and eating utensils with others
- Avoiding contact with saliva when kissing a child
- Cleaning toys, countertops, and surfaces that come into contact with a child's urine or saliva
- Using condoms during sexual contact
There is no available vaccine for preventing congenital CMV infection or CMV disease in individuals with suppressed immune systems. However, researchers are studying experimental vaccines in humans. It may be a number of years before there is a Food and Drug Administration (FDA)-approved CMV vaccine.
Akhter, Kauser. "Cytomegalovirus Workup." Medscape.com. Aug. 12, 2015. <http://emedicine.medscape.com/article/215702-workup>.
United States. Centers for Disease Control and Prevention. "Cytomegalovirus (CMV) and Congenital CMV Infection." Dec. 6, 2010. <http://www.cdc.gov/cmv/index.html>.