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February 10, 2012

Cysticercosis

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What is cysticercosis?

Cysticercosis is a systemic parasitic infestation caused by the pork tapeworm, Taenia solium. The symptoms of this illness are caused by the development of characteristic cysts (cysticerci) which most often affect the central nervous system (neurocysticercosis), skeletal muscle, eyes, and skin. Many individuals with cysticercosis never experience any symptoms (asymptomatic).

The tapeworm responsible for causing cysticercosis is endemic to many parts of the developing world, including Latin America, Asia, and sub-Saharan Africa. The incidence of cysticercosis has increased in the United States due to increased immigration from developing countries, and it is estimated that about 1,000 new cases of cysticercosis are diagnosed annually in the United States. Neurocysticercosis is a leading cause of adult-onset seizures worldwide.

Historically, the disease has been recognized since about 2000 B.C. by the Egyptians and later described in pigs by Aristotle. The disease was also recognized by Muslim physicians and is thought to be the reason for Islamic dietary prohibition of eating pork. In the 1850s, German investigators described the life cycle of T. solium.

What causes cysticercosis?

Cysticercosis is caused by the dissemination of the larval form of the pork tapeworm, Taenia solium. When the eggs of Taenia solium are ingested by humans, the tapeworm eggs hatch and the embryos penetrate the intestinal wall and reach the bloodstream. The formation of cysts in different body tissues leads to the development of symptoms, which will vary depending on the location and number of cysts.

How is cysticercosis transmitted?

Humans are the host for Taenia solium, and they may carry the tapeworm in their intestine, often without symptoms. The tapeworm eggs are periodically shed in the feces by the human reservoir, and typically pigs ingest the eggs in contaminated food or water. The pigs subsequently become infected and develop cysticerci in their body tissue. When humans eat infected raw or undercooked pork, the life cycle of the tapeworm is complete and the cycle continues.

Human cysticercosis, however, develops after humans ingest Taenia solium eggs. The eggs are typically spread via food, water, or surfaces contaminated with infected feces. Oftentimes, the eggs may be spread from the hands of infected food handlers who do not clean their hands or from foods fertilized/irrigated with water containing infected human feces. Though the source of this fecal-oral transmission often occurs from other infected individuals, it is also possible for individuals who carry the tapeworm to autoinfect themselves. The life cycle of T. solium is shown below, and pictures of the cysts in tissues can be found in the last reference listed below.

Life cycle of T. solium with resulting cysticercosis
Life cycle of T. solium with resulting cysticercosis. Photo courtesy of the CDC



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Cysticercosis

Food poisoning facts

  • Food poisoning is a common infection that affects millions of people in the United States each year.
  • Most commonly, patients complain of vomiting, diarrhea, and crampy abdominal pain.
  • People should seek medical care if they have an associated fever, blood in their stool, signs and symptoms of dehydration, or if their symptoms do not resolve after a couple of days.
  • Treatment focuses on keeping the patient well hydrated.
  • Most cases of food poisoning resolve on their own.
  • Prevention is key and depends upon keeping food preparation areas clean, good hand washing, and cooking foods thoroughly.

What is food poisoning?

Food poisoning might be described as a food borne disease. Food that contains a toxin, chemical or infectious agent (like a bacterium, virus, parasite, or prion) and cause symptoms in the body are considered types of food pois...

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