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- What is Periactin, and how does it work (mechanism of action)?
- Is it available as a generic drug?
- Do I need a prescription for this drug?
- What are the uses for Periactin?
- What are the adverse events and side effect of Periactin?
- What is the dosage for Periactin, and how should I take it?
- Which drugs or supplements interact with this medication?
- Is this drug safe to use during pregnancy or while breastfeeding?
- What else should I know about this medication?
What are the adverse events and side effect of Periactin?
Side effects of include:
- Drowsiness
- Sedation
- Dizziness
- Restlessness
- insomnia
- Tremors
- Euphoria
- Nervousness
- Irritability
- Delirium
- Seizures
- Psychosis
- Paresthesia
- Weakness
- Palpitation
- Fast heart beat
- Palpitation
- High or low blood pressure
- Anorexia
- Nausea
- Vomiting
- Diarrhea
- Constipation
- Cholestasis
- Hepatitis
- Eczema
- Itching
- Blurred vision
- Double Vision
- Ringing in the ears
- Urinary retention
- Wheezing
- Nasal stuffiness
Other side effects that have been reported include:
- Vertigo
- Sweating
- Chills
- Early menses
- Headache
- impotence
- Dryness of mouth, nose, and throat
- Facial dyskinesia
- Tightness of chest
Antihistamines may reduce mental alertness, however, they may occasionally produce excitation in children.
Patients should be warned about driving a car or operating machinery and participating in other activities that require mental alertness and motor coordination.
Antihistamines may add to the sedative effects of alcohol, hypnotics, sedatives, tranquilizers, and anti-anxiety drugs.
Antihistamines are more likely to cause dizziness, sedation, and hypotension (low blood pressure) in elderly patients.
What is the dosage for Periactin, and how should I take it?
- The recommended starting dose for adults is 4 mg every 8 hours.
- The dose range is 4 mg to 20 mg daily.
- Some patients may require up to 32 mg day. The dose should not exceed 0.5 mg/kg daily.
- The dosage for children 7 to 14 years of age should receive 4 mg 3 times daily. The maximum dose is 16 mg daily.
- Children 2 to 6 years old are treated with 2 mg three times daily and the maximum dose is 12 mg a day.
- The total daily dose may also be calculated by weight (0.25 mg/kg/day) or surface area (8 mg/m2).
Medically Reviewed by a Doctor on 5/4/2017
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Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
