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February 10, 2012
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cyclosporine - oral, Sandimmune

GENERIC NAME: CYCLOSPORINE - ORAL (sye-klo-SPORE-een)

BRAND NAME(S): Sandimmune

Warning | Medication Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage

WARNING: Cyclosporine is a drug that reduces the body's ability to fight illness/disease (an immunosuppressant), leaving patients vulnerable to infection or other problems (including cancers such as lymphoma). Using other drugs that treat organ transplant rejection along with this drug may increase these tendencies.

Cyclosporine can also cause high blood pressure and kidney problems. The risk of both problems increases with higher doses and longer treatment with this drug. Psoriasis patients who have had certain previous treatments (e.g., PUVA, UVB, coal tar, radiation therapy, methotrexate) are at increased risk to develop skin cancer. Therefore, cyclosporine must be given only under close medical supervision.

Because different brands deliver different amounts of medication, do not switch brands of cyclosporine without your doctor's permission and directions.

Laboratory tests (e.g., kidney function tests, blood tests) may be performed to monitor your progress.




Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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cyclosporine - oral, Sandimmune

When Is a Liver Transplant Needed?

Liver transplantation is considered when the liver no longer functions adequately (liver failure). Liver failure can occur suddenly (acute liver failure) as a result of infection or complications from certain medications or it can be the end result of a long-term problem. The following conditions may result in liver failure:

  • Chronic hepatitis with cirrhosis.
  • Primary biliary cirrhosis (a rare condition where the immune system inappropriately attacks and destroys the bile ducts causing liver failure).
  • Sclerosing cholangitis (scarring and narrowing of the bile ducts inside and outside of the liver causing the backup of bile in the liver which can lead to liver failure).
  • Biliary atresia (malformation of the bile ducts).
  • Alcoholism
  • Wilson's disease (a rare inherited disease with abnormal deposition of copper throughout the body, including the liver, causing it to fail)./l...

Read the Liver Transplant article »




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