cyclosporine, Restasis (cont.)

Pharmacy Author:
Medical Editor:

SIDE EFFECTS: The most common side effect of cyclosporine ophthalmic emulsion is a temporary burning sensation in the eye. Other side effects include:

PRESCRIPTION: Yes

GENERIC AVAILABLE: No

PREPARATIONS: Ophthalmic emulsion (eye drops): 0.5 mg/ml cyclosporine. Restasis is supplied in a sterile, preservative-free single-use vial.

STORAGE: Restasis should be stored at room temperature, between 15 C to 25 C (59 F to 77 F).

DOSING: One drop should be instilled in each eye twice daily. Patients may use Restasis with artificial tears or over-the-counter eye lubricants, allowing a 15 minute interval between products.

Restasis should not be used while wearing contact lenses. Patients with chronic dry eye are generally advised not to wear contact lenses. If contact lenses are worn, they should be removed before applying Restasis. Lenses may be inserted 15 minutes after applying Restasis.

The safety and effectiveness of Restasis has not been established in children below the age of 16.

DRUG INTERACTIONS: The effectiveness of Restasis may be affected if administered with other eye drops. Patients using other eye drops should consult with their eye doctor for advice. Patients may use Restasis with artificial tears or over-the-counter eye lubricants, allowing a 15 minute interval between products.

PREGNANCY: Due to the lack of conclusive safety data, Restasis should be used in pregnancy only if clearly needed. Restasis is classified as FDA pregnancy risk category C (it caused harm in studies with animals, but use during pregnancy in humans has not been adequately evaluated).

NURSING MOTHERS: It is not known if cyclosporine is excreted into breast milk following administration into the eye. Although blood levels were undetectable following ophthalmic administration, Restasis should be used cautiously during nursing.

REFERENCE: FDA Prescribing Information


Medically Reviewed by a Doctor on 4/16/2014


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