- What is cyclophosphamide, and how does it work (mechanism of action)?
- What brand names are available for cyclophosphamide?
- Is cyclophosphamide available as a generic drug?
- Do I need a prescription for cyclophosphamide?
- What are the uses for cyclophosphamide?
- What are the side effects of cyclophosphamide?
- Which drugs or supplements interact with cyclophosphamide?
- Is cyclophosphamide safe to take if I'm pregnant or breastfeeding?
- What else should I know about cyclophosphamide?
Is cyclophosphamide safe to take if I'm pregnant or breastfeeding?
- Use of cyclophosphamide during pregnancy may affect the fetus. Fetuses exposed to cyclophosphamide may be born with missing fingers, toes and a poorly-developed heart. Cyclophosphamide should not be administered during pregnancy.
- Cyclophosphamide is excreted in breast milk and could cause serious problems in the nursing infant.
What else should I know about cyclophosphamide?
What preparations of cyclophosphamide are available?
- Powder for intravenous injection: 100, 200, 500, 1000, and 2000 mg)
- Tablets: 25, 50 mg.
How should I keep cyclophosphamide stored?
- Powder and tablets should be stored at room temperature, 15 C - 30 C (59 F - 86 F).
- Solutions prepared with bacteriostatic water are usable up to 24 hours if stored at room temperature and up to 6 days if stored in the refrigerator.
- DOSING: The usual initial dose of cytoxan for adults and children is 40-50 mg/kg administered intravenously over 2-5 days in divided doses. This dose may repeated at 2-4 week intervals. The usual oral dose is 1-5 mg/kg daily. Subsequent maintenance doses are adjusted based on the response of the tumor to treatment and the side effects.
Reference: FDA Prescribing Information
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