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CYCLOPHOSPHAMIDE-ORAL, INJECTION (cont.)

PRECAUTIONS: Tell your doctor your medical history, especially of: blood disorders, liver disease, kidney disease, allergies (especially drug allergies). Avoid touching your eyes or inside your nose without first washing your hands for the duration of this treatment. Use caution with sharp objects like safety razors or nail cutters and avoid activities such as contact sports in order to lower the chance of getting cut, bruised or injured. Do not have immunizations/vaccinations without consent of your doctor and avoid contact with people who have recently received oral polio vaccine. This medication can lower your body's ability to fight an infection. Notify your doctor if you develop any signs of an infection such as fever, sore throat, rash, or chills. Cyclophosphamide is not recommended for use during pregnancy. Consult your doctor before using this drug. This drug is excreted into breast milk and should not be used while breast-feeding. Because this medication can affect the production of sperm in men, a reliable form of birth control is recommended while using this medication.

DRUG INTERACTIONS: Tell your doctor of all over-the-counter or prescription medication you may use, including: allopurinol, chloramphenicol, phenothiazines, chloroquine, succinylcholine, St John's wort. Do not start or stop any medicine without doctor or pharmacist approval.

OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly. Symptoms of overdose may include red or bloody urine, back or stomach pain, weakness, and fast heartbeat.

NOTES: Regular doctor visits are important. Frequent blood and urine tests will be done to monitor therapy and prevent side effects.

MISSED DOSE: For optimal benefits, it is important to receive each scheduled dose of this medication as directed. If you miss a dose, inform your doctor. Do not "double-up" the dose to catch up.

STORAGE: Store tablets between 36 and 77 degrees F (between 2.2 and 25 degrees C) away from moisture and sunlight. Store the powder for injection below 77 degrees F (below 25 degrees C). Refrigerate but do not freeze the oral solution.

MEDICAL ALERT: Your condition can cause complications in a medical emergency. For enrollment information call MedicAlert at 1-800-854-1166 (USA), or 1-800-668-1507 (Canada).


Last Editorial Review: 3/2/2005




Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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