cyanocobalamin (oral, Vitamin B-12)

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

What is the dosage for cyanocobalamin tablets-oral?

  • The recommended dose for treating vitamin B12 deficiency is 1000 mcg daily.
  • The recommended dose for preventing vitamin B12 deficiency is 1500 mg or 2500 mcg (sublingual tablets) daily.
  • The dose for treating hyperhomocysteinemia is 400 mg daily in combination with folic acid.

Which drugs or supplements interact with cyanocobalamin tablets-oral?

  • Chloramphenicol may decrease the effectiveness of cyanocobalamin.
  • Cancer drugs may reduce the response to cyanocobalamin treatment.
  • Use of colchicine and heavy alcohol intake for longer than 2 weeks may decrease the absorption of vitamin B12.
Medically Reviewed by a Doctor on 1/5/2016
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