cyanocobalamin

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GENERIC NAME: cyanocobalamine

BRAND NAME: Cobolin-M, Vitamin B12

DRUG CLASS AND MECHANISM: Cyanocobalamin or vitamin B12 is an essential B-vitamin. Cyanocobalamin is classified as a water-soluble vitamin. Food sources of vitamin B12 include fish, shellfish, meats, and dairy products. Vitamin B12 is necessary for growth, cell reproduction, production of red blood cells (hematopoiesis), and the production of myelin and nucleoprotein. Vitamin B12 also plays an important role in the breakdown or metabolism of fats and carbohydrates and has a role in protein synthesis. Vitamin B12 deficiency may result in anemia, gastrointestinal problems, and nerve damage. Cyanocobalamin is used to treat pernicious anemia and vitamin B12 deficiency. It is also used in the Schilling test to determine vitamin B12 absorption. Cyanocobalamin was approved by the FDA in 1949.

PRESCRIPTION: Yes

GENERIC AVAILABLE: Yes

PREPARATIONS: Cyanocobalamin injection, 1000 mcg/mL

STORAGE: Injection should be stored at 20 C - 25 C (68 F - 77 F).

PRESCRIBED FOR: Cyanocobalamin injection is used to treat vitamin B12 deficiencies due to absorption problems (malabsorption) that may be associated with conditions such as pernicious anemia, folic acid deficiency, fish tapeworm infestation, cancers of the pancreas or bowel, and otherproblems.

DOSING: (dosing may vary with individuals and with clinicians; doses presented here are examples for injection, not for oral or topical use) : Pernicious anemia (lifetime treatment required): 100 mcg intramuscularly or subcutaneously once daily for 6-7 days, followed by the same dose given on alternate days for seven doses, then every 3-4 days for another 2-3 months. Recommended maintenance dose is 100 mcg monthly for life.

Medically Reviewed by a Doctor on 10/10/2014



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