cromolyn, Nasalcrom, Gastrocrom (Intal, Opticrom are discontinued)

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

Asthma Attack Treatment

SIDE EFFECTS: Common side effects include:

Allergic reactions also can occur. Increased spasm of the breathing tubes (bronchospasm), throat irritation, and cough are the most common side effects from oral inhalation of cromolyn. Taking a beta-adrenergic bronchodilator (for example, albuterol) prior to the cromolyn can prevent these side effects. Cromolyn intranasal spray can produce sneezing and nasal irritation, but these effects generally are short-lived following each application. Use of cromolyn eye drops can produce irritation of the eye. This effect also is generally short-lived.

PRESCRIPTION: No (nasal solution). Yes (other forms)

GENERIC AVAILABLE: Yes

PREPARATIONS: Intranasal Spray: 5.2 mg/spray; Nebulized Solution: 10 mg/ml: Opthalmic Solution: 4% (1.6 mg/drop); Oral Concentrate: 100 mg/5 ml.

STORAGE: Cromolyn should be kept at room temperature, 20 C - 25 C (68 F - 77 F).

DOSING: Cromolyn nebulized solution: 20 mg inhaled via nebulizer 2 or 4 times daily. Intranasal spray: Adults and children 2 years of age and older can use one spray in each nostril three or four times daily. If necessary, the dose may be increased to 6 times daily.

Ophthalmic (eye) solution: The usual dose in adults and children 4 years of age and older is one or two drops in each eye 4 to 6 times per day. Relief may be evident within a few days but several weeks of therapy may be required.

Oral concentrate solution: The recommended dose is 200 mg 4 times daily 30 minutes prior to meals.

DRUG INTERACTIONS: No drug interactions have been described with cromolyn.

PREGNANCY: There are no adequate studies in pregnant women.

NURSING MOTHERS: It is not known whether cromolyn is secreted into breast milk.

Medically reviewed by Eni Williams, PharmD

Reference: FDA Prescribing Information

Medically Reviewed by a Doctor on 5/22/2015

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