SIDE EFFECTS: Common side effects include:
Allergic reactions also can occur. Increased spasm of the breathing tubes (bronchospasm), throat irritation, and cough are the most common side effects from oral inhalation of cromolyn. Taking a beta-adrenergic bronchodilator (for example, albuterol) prior to the cromolyn can prevent these side effects. Cromolyn intranasal spray can produce sneezing and nasal irritation, but these effects generally are short-lived following each application. Use of cromolyn eye drops can produce irritation of the eye. This effect also is generally short-lived.
PRESCRIPTION: No (nasal solution). Yes (other forms)
GENERIC AVAILABLE: Yes
PREPARATIONS: Intranasal Spray: 5.2 mg/spray; Nebulized Solution: 10 mg/ml: Opthalmic Solution: 4% (1.6 mg/drop); Oral Concentrate: 100 mg/5 ml.
STORAGE: Cromolyn should be kept at room temperature, 20 C - 25 C (68 F - 77 F).
DOSING: Cromolyn nebulized solution: 20 mg inhaled via nebulizer 2 or 4 times daily. Intranasal spray: Adults and children 2 years of age and older can use one spray in each nostril three or four times daily. If necessary, the dose may be increased to 6 times daily.
Ophthalmic (eye) solution: The usual dose in adults and children 4 years of age and older is one or two drops in each eye 4 to 6 times per day. Relief may be evident within a few days but several weeks of therapy may be required.
Oral concentrate solution: The recommended dose is 200 mg 4 times daily 30 minutes prior to meals.
DRUG INTERACTIONS: No drug interactions have been described with cromolyn.
PREGNANCY: There are no adequate studies in pregnant women.
NURSING MOTHERS: It is not known whether cromolyn is secreted into breast milk.
Medically reviewed by Eni Williams, PharmD
Reference: FDA Prescribing Information
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