Creatinine Blood Test

  • Medical Author:
    Charles Patrick Davis, MD, PhD

    Dr. Charles "Pat" Davis, MD, PhD, is a board certified Emergency Medicine doctor who currently practices as a consultant and staff member for hospitals. He has a PhD in Microbiology (UT at Austin), and the MD (Univ. Texas Medical Branch, Galveston). He is a Clinical Professor (retired) in the Division of Emergency Medicine, UT Health Science Center at San Antonio, and has been the Chief of Emergency Medicine at UT Medical Branch and at UTHSCSA with over 250 publications.

  • Medical Editor: William C. Shiel Jr., MD, FACP, FACR
    William C. Shiel Jr., MD, FACP, FACR

    William C. Shiel Jr., MD, FACP, FACR

    Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.

What are the reasons for elevated blood creatinine?

Any condition that impairs the function of the kidneys is likely to raise the creatinine level in the blood. It is important to recognize whether the process leading to kidney dysfunction (kidney failure, azotemia) is longstanding or recent. Recent elevations may be more easily treated and reversed.

The most common causes of longstanding (chronic) kidney disease in adults are

Other causes of elevated blood creatinine levels are:

  • Certain drugs (for example,cimetidine [Bactrim]) can sometimes cause abnormally elevated creatinine levels.
  • Serum creatinine can also transiently increase after ingestion of a large amount of dietary meat; thus,nutrition can sometimes play a role in creatinine measurement.
  • Kidney infections,rhabdomyolysis (abnormal muscle breakdown) and urinary tract obstruction may also elevate creatinine levels.
Reviewed on 10/12/2016
References
Medically reviewed by John A. Daller, MD; American Board of Surgery with subspecialty certification in surgical critical care

REFERENCES:

MedscapeReference.com. Creatinine Clearance.

Lifeoptions.org. Lab Values Explained.

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