Creatine

How does Creatine work?

Creatine is involved in making the energy muscles need to work.

Are there safety concerns?

Creatine seems to be safe for most people when used at recommended doses. Creatine can cause stomach pain, nausea, diarrhea, and muscle cramping.

Creatine causes muscles to draw water from the rest of your body. Be sure to drink extra water to make up for this. Also, if you are taking creatine, don't exercise in the heat. It might cause you to become dehydrated.

Many people who use creatine gain weight. This is because creatine causes the muscles to hold water, not because it actually builds muscle.

There is some concern that combining creatine with caffeine and the herb ephedra (also called Ma Huang) might increase the chance of having serious side effects such as stroke.

There is concern that creatine might cause heart arrhythmia in some people. But more information is needed to know if creatine can cause this problem.

There is concern that creatine might cause a skin condition called pigmented purpuric dermatosis in some people. But more information is needed to know if creatine can cause this problem.

Do not use creatine if:
  • You are pregnant or breast-feeding.
  • You have kidney disease.
  • You have diabetes, because you might have a higher chance of developing kidney disease.

Therapeutic Research Faculty copyright

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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