Coxsackie Virus (cont.)

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What is the prognosis of coxsackie virus infections?

Until recently, the general prognosis for most patients with coxsackie infections was excellent, with most children making a complete recovery without needing any supportive care (hospitalization). However, this prognosis may be changing as evidenced by the outbreak in Alabama in 2011-2012 that required 12% percent of children to be hospitalized for supportive care. Only rarely do patients suffer poor outcomes with complications of meningitis, pericarditis, or encephalitis. Unfortunately, infants and young children infected with EV-71 have a prognosis that may vary from good to poor.


Blomqvist, S., P. Kemola, P., S. Kaijalainen, et al. "Co-circulation of Coxsackieviruses A6 and A10 in Hand, Foot and Mouth Disease Outbreak in Finland." J. Clin. Virol. 48.1 May 2010: 49-54.

Kaushik, Parul. "Coxsackieviruses." Apr. 29, 2014. <>.

Nervi, Stephen J. "Hand-Foot-and-Mouth Disease." Apr. 17, 2014. <>.

Richer, M., and M. Horwitz. "Coxsackievirus Infection as an Environmental Factor in the Etiology of Type 1 Diabetes." Autoimmun. Rev. 8.7 June 2009: 611-615.

United States. Centers for Disease Control and Prevention. "Hand, Foot, and Mouth Disease." May 22, 2013. <>.

United States. Centers for Disease Control and Prevention. "Notes from the Field: Severe Hand, Foot, and Mouth Disease Associated with Coxsackievirus A6 -- Alabama, Connecticut, California, and Nevada, November 2011–February 2012." MMWR 61.12 Mar. 30, 2012: 213-214. <>.

Medically Reviewed by a Doctor on 7/11/2014

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