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coumarin-type drugs-oral (cont.)

PRECAUTIONS: Before taking this drug, tell your doctor your medical history, especially of: bleeding problems (ulcers or lengthy or heavy menstrual periods), diabetes, liver or kidney disease, high blood pressure, arthritis, thyroid problems, any infection, recent surgery, any allergies. Do not switch to a different brand name of this drug product because it may differ in effect. It is important that all doctors and dentists treating you know that you take this drug so that they can avoid prescribing other drugs that may interfere with its effect. Do not stop using other medications you are currently using unless directed to do so by your doctor. Do not start taking any nonprescription drugs including vitamins and nutritional supplements without consulting your doctor. If you have an illness that causes vomiting, diarrhea, or fever for more than a few days, contact your doctor. These problems can change the effect of this drug. Limit your consumption of alcoholic beverages. Ask your doctor how much, if any, alcohol you may consume. Patients taking this drug should avoid sudden changes in dietary habits. They should avoid ingesting unusual increases of foods rich in Vitamin K (liver, broccoli, cauliflower, cabbage, kale, spinach and other green leafy vegetables, green beans, green tea, some cheeses and some vitamin supplements). They should also avoid strictly vegetarian diets that consist of foods high in Vitamin K content. This drug must not be used during pregnancy. If you become pregnant or think you may be pregnant, inform your doctor immediately. This drug is excreted into breast milk. Though no problems to the infant have been noted to date, consult your doctor before breast-feeding.

DRUG INTERACTIONS: Tell your doctor of all prescription and nonprescription drugs you may use, especially of: aspirin or aspirin-like drugs (salicylates), anabolic steroids, barbiturates, clofibrate, phenylbutazone, disulfiram, cimetidine, sulfa-drugs, metronidazole, vitamin E, cholestyramine, phenytoin, erythromycin-like antibiotics, propylthiouracil, injectable antibiotics, griseofulvin, ethchlorvynol, quinidine, quinine, thyroid medication, allopurinol, glucagon, rifampin, glutethimide, aminoglutethimide, chloramphenicol, carbamazepine, vitamin K (or its derivatives), dextrothyroxine, anti-inflammatory medication used for arthritis or fever reduction, birth control pills, dong quai, ginkgo biloba, ginseng. Do not start or stop any medicine without doctor or pharmacist approval.



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