cosyntropin (Cortrosyn) (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

DOSING: The initial dose for adults is based on what the drug is being used for and whether it is being given intravenously or intramuscularly. For example, the intravenous dose in diagnosing adrenocortical insufficiency is 0.25 mg. Initial doses of 1 mg intramuscularly may be used when transferring from corticosteroids.

DRUG INTERACTIONS: Cosyntropin may increase the electrolyte loss during diuretic therapy.

PREGNANCY: Cosyntropin is a Category C drug. There are no adequate studies of cosyntropin in pregnant women.

NURSING MOTHERS: It is unknown whether cosyntropin is excreted in breast milk and, therefore, should be used cautiously by mothers who are nursing.

SIDE EFFECTS: Adverse effects associated with the use of cosyntropin include slowed heart rate, high blood pressure, edema (fluid buildup) in limbs, and rapid heartbeat. Other adverse effects include rash as well as redness at the injection site. Side effects associated with corticosteroid use are also commonly reported with cosyntropin use. There have been rare reports of anaphylactic reactions.

REFERENCE: FDA Prescribing Information.

Medically Reviewed by a Doctor on 8/15/2014

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