cosyntropin (Cortrosyn)

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GENERIC NAME: cosyntropin

BRAND NAMES: Cortrosyn

DRUG CLASS AND MECHANISM: Cosyntropin is a manufactured version of the body's natural adrenocorticotropin hormone (ACTH). ACTH is produced by the pituitary gland in the brain. It stimulates the adrenal gland to release steroids including hydrocortisone and cortisone, androgens, as well as aldosterone. Cosyntropin has the same activity as ACTH. The FDA approved Cosyntropin in April 1970.



PREPARATIONS: Powder (with and without preservatives) 0.25 mg; Solution: 0.25 mg/mL in 1 mL vial

STORAGE: Cosyntropin powder should be stored at room temperature between 15 C to 30 C (59 F to 86 F). Cosyntropin solution and suspension should be stored under refrigeration between 2 C to 8 C (36 F to 46 F) and protected from light and freezing. Infusions are stable for 12 hours at room temperature.

PRESCRIBED FOR: Cosyntropin is used in diagnostic tests to distinguish the presence of primary (adrenal dysfunction) versus secondary (pituitary dysfunction) adrenocortical insufficiency. The intramuscular injection may be used for other disease processes including collagen, dermatologic, endocrine, ocular, and hemolytic disorders.

Medically Reviewed by a Doctor on 8/15/2014

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