Patient Comments: Cortisone Injection - Side Effects

What side effects (if any) did you experience with your cortisone injection?

Comment from: Maureen, 45-54 Female (Patient) Published: July 09

On July 7th I had a corticosteroid injection in my left ankle as the result of a break. While the needle itself was not painful, the serum had a strange 'pressure' feel to it. I felt great immediately following the injection but as I was driving home (less than 10 minutes away) I started to feel a burning sensation in the ankle where the serum was released. I was told that it would get worse at first and that I may experience numbness but it will subside in a few days.

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Comment from: sdmom, 55-64 Female (Patient) Published: July 01

I had a cortisone shot in my shoulder joint as I had been experiencing terrible pain due to adhesive capsulitis (frozen shoulder). Unfortunately, I had a horrible reaction to the shot (post-injection flare) and about 2 hours after the shot after the numbing agent had worn off, I had the worst pain ever imaginable. My arm and shoulder felt like it was on fire and any little movement even of my fingers sent a shooting pain throughout my arm and shoulder. I had to take opiates and codeine the entire night and it didn't help at all. I didn't get any relief from the pain for 24 hours. It did eventually went away but it made me think twice about ever doing this again.

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Comment from: Gillian, 55-64 Female (Patient) Published: June 30

After having been told for eight years that I have diabetes almost to the stage of needing injectable insulin, my doctor performed a peptide blood test on me, found my insulin was very high, and that my diabetes is producing plenty of insulin! I am not diabetic, I am insulin resistant. Now I have to rethink my medications. Why am I taking glipizide and Januvia to force my pancreas to manufacture insulin if I already am above the normal scale for insulin!

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Comment from: Isabella, 75 or over Female (Patient) Published: June 26

I had a cortisone injection in my knee yesterday which was fine, but today I have flushing of my cheeks and chest. I wonder if this is one of the side effects my general physician didn't warn me of any.

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Comment from: bobolink, 45-54 Female (Patient) Published: June 24

I had two cortisone injections into finger joints to relieve the inflammation of osteoarthritis. Two days later I noticed I was heading into a depression. I had been feeling fine and there was no other reason or trigger for the depression. Four days later I cannot shake the malaise. They don't tell you of this for local injections, though the link between mood and steroid use is well established.

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Comment from: Jaking, 35-44 Female (Patient) Published: June 17

I had a cortisone injection into my knee yesterday at 1:00. By 5:00 it hurt so badly I was crying. My whole body locked up (meaning all my muscles were tight and I couldn't get them to relax), and relaxing seemed to make the pain worse. But not relaxing was not helping either. I had to take 2 tramadol pain pills (left over from my knee surgery 6 months prior to injection), a muscle relaxer and 2 Tylenol before I had any relief. I was shivering, shaking and my teeth were chattering. I had no control over the shivering or chattering teeth. I checked in mentally and emotionally to see if I was having an anxiety attack or something but I don't believe I was. Internally I felt calm and my blood pressure and pulse were low/normal. I don't know if it was just a sever flare or allergic reaction maybe. Today my knee is sore and tight which is usual for me after an injection for a day or two. I left a message with my surgeon and physical therapist, I'm waiting for a call back.

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Comment from: Roxanne, 65-74 Female (Patient) Published: June 09

After experiencing knee pain that did not resolve after a couple of weeks I saw an orthopedic doctor and he ordered an MRI which did not show any tears. He gave me a cortisone shot in my left knee and since that time I have experienced extreme chest pressure during walking even a short distance (at a slow pace), and when riding my bike. I checked my blood pressure and it is running around 156/96. I did not experience this until after the injection.

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Patient Comments

Viewers share their comments

Cortisone Injection - Experience Question: Please describe your experience with a cortisone injection.
Cortisone Injection - Knee and Hip Question: Share your experience with cortisone injections in your hip or knee.

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